The Parenteral “Numbers Game”—Newer Ways of Looking at Particulate Contamination |
PDA Journal of Pharmaceutical Science and Technology Skip to main content Main menu …

Particulate matter may be described as insoluble material (s) inevitably present in injectable
solutions. Processing conditions for parenteral solutions are designed to substantially …

Clinicians have had concerns about particulate matter contamination of injectable drug
products since the development of the earliest intravenous therapeutics. All parenteral …

Particulate matter (PM) associated with pharmaceutical systems is in large part unwanted
contamination in sterile products for which there are compendial guideline methods and …

Theoretical predictions and computer simulations indicate that it may be impossible to
achieve values of the coefficient of variation usually found in large volume parenterals (LVP) …

Maxime Perez is a hospital and university pharmacist at the Pharmacy Institute of the
University Hospital of Lille since November 2015 with special interest in clinical pharmacy …

The pharmaceutical applications of powder technology have long been recognized. Yet
while many books focus on aspects of powder formation and behavior, there has been no …

Concern over the recent introduction of limits for allowable particulate contamination in small
volume parenterals by the United States Pharmacopeia XXI has drawn attention to the …

The presence of foreign visible and sub visible particulate matter in parenteral formulation
affects its biological safety. Hence there is need to proper check on the sources of the …

Protein pharmaceuticals have become an important part of modern therapeutics. Of the top
50 pharmaceutical companies, 30 are currently involved in biologics, and 27% of the US …