Prefilled syringes and autoinjectors are becoming increasingly common for parenteral drug
administration primarily due to the convenience they offer to the patients. Successful …

Accurate injection time prediction is essential in developing spring-driven autoinjector
devices since the drug delivery is expected to finish within seconds to bring convenience …

Use of prefilled syringes to self-administer biologics via subcutaneous administration
provides convenience to patients. The barrel interior of prefilled syringes is typically coated …

The design of injection devices, including prefilled syringes (PFSs) and autoinjectors,
requires an understanding of the optimization of injection conditions. The injection of highly …

There is an increasing demand for advanced injection devices that bring benefits around
self-administration and ease of use, and also for injectors that work with new biological …

Infusion therapy is medically and technically challenging and frequently associated with
medical errors. When administering pharmaceuticals by means of infusion, dosing errors …

This study focuses on developing a predictive dynamic model for spring-driven
autoinjectors. The values of unknown physical parameters, such as the heat convection …

Background This work describes an advanced physics-based mathematical model that
accurately predicts autoinjector injection time. Autoinjectors are a well-established …

Abstract Development of injection devices for subcutaneous drug administration requires a
detailed understanding of user capability and forces occurring during the drug …

Spring-actuated autoinjectors delivering viscous drug solutions resulting from large drug
concentrations require large spring forces which can create high peak pressures and …