Comment and completion: implementation of parallelism testing for four-parameter logistic model in bioassays

P Sondag, R Joie, H Yang - PDA journal of pharmaceutical science …, 2015 - journal.pda.org
Parallelism testing between two four-parameter logistic curves has been widely discussed
over the last decade. Current tests available in common statistical software used in …

Implementation of parallelism testing for four-parameter logistic model in bioassays

H Yang, HJ Kim, L Zhang, RJ Strouse… - PDA journal of …, 2012 - journal.pda.org
Parallelism is a prerequisite for the determination of relative potency in bioactivity assays. It
involves the testing of similarity between a pair of dose-response curves of reference …

Testing for parallelism in the heteroscedastic four-parameter logistic model

K Sidik, JN Jonkman - Journal of biopharmaceutical statistics, 2016 - Taylor & Francis
For bioassay data in drug discovery and development, it is often important to test for
parallelism of the mean response curves for two preparations, such as a test sample and a …

Equivalence testing for parallelism in the four-parameter logistic model

JN Jonkman, K Sidik - Journal of biopharmaceutical statistics, 2009 - Taylor & Francis
For assay or dose-response data in drug discovery, it is often important to test for parallelism
of the response curves for two preparations, such as a test drug and a standard drug, in …

A Bayesian approach to parallelism testing in bioassay

SJ Novick, H Yang, JJ Peterson - Statistics in biopharmaceutical …, 2012 - Taylor & Francis
Parallelism is a prerequisite for the determination of relative potency in bioassays. It involves
testing of similarity between a pair of dose–response curves of a reference standard and a …

Evaluations of parallelism testing methods using ROC analysis

H Yang, L Zhang - Statistics in Biopharmaceutical Research, 2012 - Taylor & Francis
Parallelism is often a prerequisite in relative potency determination using bioassays. It
involves testing the similarity between a pair of dose–response curves of reference standard …

Parallelism in practice: approaches to parallelism in bioassays

K Fleetwood, F Bursa, A Yellowlees - PDA journal of …, 2015 - journal.pda.org
Relative potency bioassays are used to estimate the potency of a test biological product
relative to a standard or reference product. It is established practice to assess the parallelism …

A curve similarity approach to parallelism testing in bioassay

P Faya, AP Rauk, KL Griffiths… - Journal of …, 2020 - Taylor & Francis
Potency determination via bioassay is a relative measure that requires an evaluation of
parallelism between the dose–response relationships of a reference standard and a sample …

A fast and reliable test for parallelism in bioassay

S Novick, H Yang - Journal of biopharmaceutical statistics, 2019 - Taylor & Francis
Parallelism in bioassay is a synonym of similarity between two concentration–response
curves. Before the determination of relative potency in bioassays, it is necessary to test for …

Measuring parallelism, linearity, and relative potency in bioassay and immunoassay data

PG Gottschalk, JR Dunn - Journal of biopharmaceutical statistics, 2005 - Taylor & Francis
There is often a need to determine parallelism or linearity between pairs of dose–response
data sets for various biological applications. This article describes a technique based on a …