This study aims to investigate the causes of different sources of weight variation of capsules
and thereby to suggest a suitable control scheme to improve productivity in a …

The aim of this work was to investigate the mean fill weight control of a continuous capsule-
filling process, whether it is possible to derive controller settings from an appendant process …

This study is the second in a series that examines the characterizing and selection of
suitable grades of lactose for capsule formulation development. Based upon the previous …

The overall objective of this study is to use the experimental design approaches to
investigate the relationship between quality uniformity and formulation parameters such as …

Today's pharmaceutical industry is improving its ability to become agile at the manufacturing
of clinical supplies. One approach consists of using Material-Sparing-Formulation for early …

The Food and Drug Administration provides regulations for combination products. The
medical device industry needs to comply with these regulations specifically in products …

[eng] In the pharmaceutical industry a minor mistake can cause huge consequences, both
sanitary and economic. Therefore, rules of quality have to be well followed and all the …

Since the origins of the agency, the Food and Drugs Administration (FDA), a scientific,
regulatory, and public health agency had been dedicated to consumer protection. The FDA …

The influence of the compression setting ratio on the capsule fill weigth variability has been
assessed for a series of particle size fractions of Avicel, calcium carbonate, lactose, maize …

Improving the yield of batch-wise production is an increasingly important topic for the
pharmaceutical industry; reasons for that include the rising public pressure on drug prices as …