We evaluated the efficacy of different neutralizing solutions for use in disinfectant efficacy
assays. Our approach used comparisons between the recoveries of low inocula in different …

In-use testing of disinfectants is necessary to ensure efficacy over time. The current official
procedure for testing disinfectants, the Association of Official Analytical Chemists (AOAC) …

Aims: To develop a novel, rapid method for testing the ability of quenching agents to
neutralize disinfectants. Methods and Results: Tests were performed to determine the …

Background There has been a dramatic increase in the number of hospital-acquired
infections, which is linked to the pandemic of multidrug resistance. Clinical environments …

A quantitative assay using a neutralization medium was developed to evaluate fungicidal
activity of disinfectants. Concentrated Dey-Engley neutralizing broth was used in this study …

Disinfectants and antiseptics are important weapons to reduce the number of micro-
organisms and thus limit the number of infections. Different methods of antimicrobial activity …

For well over a decade, many deficiencies have been identified in current AOAC methods
used to assess the microbicidal activities of chemical disinfectants on medical devices and …

Background Multidrug-resistant gram-negative bacteria (MDR-GNB) constitute a threat to
health care worldwide. Disinfectants are used to prevent and control the spread of MDR …

BACKGROUND: A considerable number of tests are recommended in the literature to
evaluate in vitro commercial chemical solutions. The variety of tests reflects their limitations …

For the development and approval of disinfectants, laboratory tests which combine
repeatability and reproducibility with relevance to practical conditions are required to ensure …