Sorption of parabens by fluoropolymer or fluoropolymer laminated flexible tubing

SM Bahal, JM Romansky - PDA Journal of Pharmaceutical Science …, 2001 - journal.pda.org
Earlier studies using methylparaben and propylparaben showed extensive losses due to
sorption by silicone, polyvinyl chloride, and other flexible tubing. As much as 100% loss of …

Sorption of parabens by flexible tubings

SM Bahal, JM Romansky - Pharmaceutical development and …, 2001 - Taylor & Francis
Flexible tubings are extensively used in pharmaceuticals, food industry, and in hospitals.
This study was undertaken to compare various flexible tubings to determine their sorption …

Sorption of benzoic acid, sorbic acid, benzyl alcohol, and benzalkonium chloride by flexible tubing

SM Bahal, JM Romansky - Pharmaceutical development and …, 2002 - Taylor & Francis
Earlier studies using methylparaben, propylparaben, and several types of flexible tubing
showed that the parabens are sorbed by a number of commonly used tubing. The sorption …

Adsorption of Esters of p-Hydroxybenzoic Acid by Filter Membranes: Mechanism and Effect of Formulation and Processing Parameters

T Bin, L McCrosky, AK Kulshreshtha… - Pharmaceutical …, 2000 - Taylor & Francis
The adsorption of esters of p-hydroxybenzoic acid (parabens) by filter membranes was
studied by a flow-through technique. The hydrophobic effect was the major mechanism of …

Acceleration of paraben sorption to polyethylene terephthalate: a freeze-thaw phenomenon

PA Bergquist, EA Kemp, RA Seburg… - PDA Journal of …, 2006 - journal.pda.org
The evaluation of preservative stability in a formulation throughout its life cycle (production,
shipping, and storage) is an important part of product development and essential to ensuring …

Mechanistic Insights into Propylparaben Sorption on Polyvinyl Chloride

CEC Soto, R Sengupta, I Gonzales, S Schupp… - Journal of …, 2024 - Elsevier
The mechanism of loss of propylparaben potency from formulations when in contact with
polyvinyl chloride has been determined. It is caused by the adsorption of propylparaben …

The effect of co-solvents on the antibacterial activity of paraben preservatives

RM Darwish, SF Bloomfield - International journal of pharmaceutics, 1995 - Elsevier
The solubility of methyl and propyl p-hydroxybenzoate esters (parabens) in 3 M
concentrations of the co-solvents ethanol, propylene glycol and glycerol was investigated …

[PDF][PDF] Determination of Preservative Parabens in Oral and Injection Formulations by HPLC

S Antakli, R Kabani, D Shawa - Asian Journal of Chemistry, 2013 - researchgate.net
Two new HPLC-UV methods are described for determining methyl paraben and propyl
paraben, methyl paraben sodium and propyl paraben sodium in oral and injection …

Release of propyl paraben from a polymer coating into water and food simulating solvents for antimicrobial packaging applications

D Chung, SE Papadakis, KL Yam - Journal of Food Processing …, 2001 - Wiley Online Library
The release phenomena of propyl paraben from a polymer coating to water and three food
simulating solvents (10% aqueous ethanol, 50% aqueous ethanol, n‐heptane) were studied …

Sorption of antimicrobial agents in blow-fill-seal packs

A Amin, S Chauhan, M Dare… - Pharmaceutical …, 2012 - Taylor & Francis
The present work studies the interaction of methyl paraben (MPB) and propyl paraben
(PPB), two widely used antimicrobial agents in multi-dose ophthalmic formulations, with 5 …