The 1990 International Conference on Particle Detection, Metrology, and Control (February,
1990) jointly sponsored by the Parenteral Drug Association, Inc. and The Institute for …

The problem of detecting visible particles in parenteral fluids has been of concern to the
pharmaceutical industry for many years. lS2 A number of attempts have been made to solve …

Our evaluation of electronic liquid-borne particle counter systems has shown that, for
accurate measurement of particulate matter in injections, the half count values of voltage …

The international drive to achieve higher quality and improved cost effectiveness in
parenteral products has achieved an apparent concensus concerning the utility and …

The prerequisites for estimating the effect of signal coincidence on both particle
undercounting and the injection of false counts in the implementation of USP 788 …

USP objective tests for particle contamination in injectable fluids are based on counts of
single particles in a specified test volume. Accuracy standards for these tests must therefore …

Theoretical sphericity factors for objects of various geometric shapes were calculated based
on ideal performance of a light blockage detector, an electrolyte displacement sensor, and …

The following paper was presented at the 1999 PDA International Conference in Tokyo,
Japan February 24, 1999. The paper was written in response to the recent well-publicized …

Particulate contamination standards are the subject of monographs in many
pharmacopaeias including the BP and USP In general the standards allow for a range of …

The current pharmacopoeiol limit tests for particulate contamination in parenteral solutions
are critically reviewed and likely sources of contamination ore then discussed in relation to …