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Review ArticleREVIEW ARTICLE

Extractable Substances from Plastic Materials Used in Solution Contact Applications: An Updated Review

Dennis Jenke
PDA Journal of Pharmaceutical Science and Technology May 2006, 60 (3) 191-207;
Dennis Jenke
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Abstract

This is an updated review related to the identification and/or accumulation of organic and inorganic extractable substances from di(2-ethylhexyl) phthalate (DEHP)-plasticized polyvinyl chloride (PVC), polyolefin, and various other plastic materials. The review considers the identification of such extractables, their reported levels in material extracts, and the strategic issues associated with investigations of extractables/leachables.

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  • Copyright © Parenteral Drug Association. All rights reserved.
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PDA Journal of Pharmaceutical Science and Technology
Vol. 60, Issue 3
May/June 2006
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Extractable Substances from Plastic Materials Used in Solution Contact Applications: An Updated Review
Dennis Jenke
PDA Journal of Pharmaceutical Science and Technology May 2006, 60 (3) 191-207;
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  • Materials in Manufacturing and Packaging Systems as Sources of Elemental Impurities in Packaged Drug Products: A Literature Review
  • The Product Quality Research Institute (PQRI) Leachables and Extractables Working Group Initiatives for Parenteral and Ophthalmic Drug Product (PODP)
  • A Compilation of Metals and Trace Elements Extracted from Materials Relevant to Pharmaceutical Applications such as Packaging Systems and Devices
  • Identification of a Leachable Compound Detrimental to Cell Growth in Single-Use Bioprocess Containers
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© 2025 PDA Journal of Pharmaceutical Science and Technology Print ISSN: 1079-7440  Digital ISSN: 1948-2124

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Extractable Substances from Plastic Materials Used in Solution Contact Applications: An Updated Review
Dennis Jenke
PDA Journal of Pharmaceutical Science and Technology May 2006, 60 (3) 191-207;

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