Abstract
The United States Pharmacopeia has proposed particulate matter limits for small volume parenterals using a HIAC particle size analyzer. This paper compares the results from a HIAC particle size analyzer, an automated image analyzer and the Pharmaceutical Manufacturers Association (PMA) membrane microscopic method. Ten lots of a dry powder antibiotic were used for the analysis. No correlation is readily evident among the different methods of particle size analysis. The HIAC results are generally lower than the PMA membrane microscopic method and those of the automated image analyzer.
- Received May 20, 1985.
- Accepted February 4, 1986.
- Copyright © Parenteral Drug Association. All rights reserved.
PDA members receive access to all articles published in the current year and previous volume year. Institutional subscribers received access to all content. Log in below to receive access to this article if you are either of these.
If you are neither or you are a PDA member trying to access an article outside of your membership license, then you must purchase access to this article (below). If you do not have a username or password for JPST, you will be required to create an account prior to purchasing.
Full issue PDFs are for PDA members only.
Note to pda.org users
The PDA and PDA bookstore websites (www.pda.org and www.pda.org/bookstore) are separate websites from the PDA JPST website. When you first join PDA, your initial UserID and Password are sent to HighWirePress to create your PDA JPST account. Subsequent UserrID and Password changes required at the PDA websites will not pass on to PDA JPST and vice versa. If you forget your PDA JPST UserID and/or Password, you can request help to retrieve UserID and reset Password below.