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Research ArticleRESEARCH

Mechanistic Studies of Glass Vial Breakage for Frozen Formulations. II. Vial Breakage Caused by Amorphous Protein Formulations

Ge Jiang, Mike Akers, Manish Jain, Jeremy Guo, Adrian Distler, Rob Swift, Manpreet-Vick S. Wadhwa, Feroz Jameel, Sugu Patro and Erwin Freund
PDA Journal of Pharmaceutical Science and Technology November 2007, 61 (6) 452-460;
Ge Jiang
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  • For correspondence: gjiang@amgen.com
Mike Akers
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Manish Jain
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Jeremy Guo
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Adrian Distler
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Rob Swift
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Manpreet-Vick S. Wadhwa
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Feroz Jameel
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Sugu Patro
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Erwin Freund
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PDA Journal of Pharmaceutical Science and Technology
Vol. 61, Issue 6
November/December 2007
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Mechanistic Studies of Glass Vial Breakage for Frozen Formulations. II. Vial Breakage Caused by Amorphous Protein Formulations
Ge Jiang, Mike Akers, Manish Jain, Jeremy Guo, Adrian Distler, Rob Swift, Manpreet-Vick S. Wadhwa, Feroz Jameel, Sugu Patro, Erwin Freund
PDA Journal of Pharmaceutical Science and Technology Nov 2007, 61 (6) 452-460;

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Mechanistic Studies of Glass Vial Breakage for Frozen Formulations. II. Vial Breakage Caused by Amorphous Protein Formulations
Ge Jiang, Mike Akers, Manish Jain, Jeremy Guo, Adrian Distler, Rob Swift, Manpreet-Vick S. Wadhwa, Feroz Jameel, Sugu Patro, Erwin Freund
PDA Journal of Pharmaceutical Science and Technology Nov 2007, 61 (6) 452-460;
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Cited By...

  • Novel Mechanism of Glass Delamination in Type 1A Borosilicate Vials Containing Frozen Protein Formulations
  • Investigation of Freeze/Thaw-Related Quality Attributes of a Liquid Biopharmaceutical Formulation: The Role of Saccharide Excipients
  • Effects of Subzero Temperature Exposure and Supercooling on Glass Vial Breakage: Risk Management and Other Applications in Cold Chain Distribution
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