Skip to main content

Main menu

  • Home
  • Content
    • Current Issue
    • Past Issues
    • Accepted Articles
    • Email Alerts
    • RSS
    • Terms of Use
  • About PDA JPST
    • JPST Editors and Editorial Board
    • About/Vision/Mission
    • Paper of the Year
  • Author & Reviewer Resources
    • Author Resources / Submit
    • Reviewer Resources
  • JPST Access and Subscriptions
    • PDA Members
    • Institutional Subscriptions
    • Nonmember Access
  • Support
    • Join PDA
    • Contact
    • Feedback
    • Advertising
    • CiteTrack
  • .
    • Visit PDA
    • PDA Letter
    • Technical Reports
    • news uPDATe
    • Bookstore

User menu

  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
PDA Journal of Pharmaceutical Science and Technology
  • .
    • Visit PDA
    • PDA Letter
    • Technical Reports
    • news uPDATe
    • Bookstore
  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart
PDA Journal of Pharmaceutical Science and Technology

Advanced Search

  • Home
  • Content
    • Current Issue
    • Past Issues
    • Accepted Articles
    • Email Alerts
    • RSS
    • Terms of Use
  • About PDA JPST
    • JPST Editors and Editorial Board
    • About/Vision/Mission
    • Paper of the Year
  • Author & Reviewer Resources
    • Author Resources / Submit
    • Reviewer Resources
  • JPST Access and Subscriptions
    • PDA Members
    • Institutional Subscriptions
    • Nonmember Access
  • Support
    • Join PDA
    • Contact
    • Feedback
    • Advertising
    • CiteTrack
  • Follow pda on Twitter
  • Visit PDA on LinkedIn
  • Visit pda on Facebook
Research ArticleRESEARCH

Evaluation of Disinfecting Procedures for Aseptic Transfer in Hospital Pharmacy Departments

Manita Mehmi, Lindsay J. Marshall, Peter A. Lambert and Julian C. Smith
PDA Journal of Pharmaceutical Science and Technology March 2009, 63 (2) 123-138;
Manita Mehmi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lindsay J. Marshall
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter A. Lambert
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Julian C. Smith
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: julian.smith@CardiffandVale.wales.nhs.uk
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Cockroft M. G.,
    2. Hepworth D.,
    3. Rhodes J. C.,
    4. Addison P.,
    5. Beaney A. M.,
    Validation of liquid disinfection techniques for transfer of components into hospital pharmacy cleanrooms. Hospital Pharmacist 2001, 8, 226– 232.
    OpenUrl
  2. 2.↵
    1. Stubbs S.,
    Step-by-step selection of cleanroom disinfectants. Hospital Pharmacy Europe 2005, 18, 25– 26.
    OpenUrl
  3. 3.↵
    1. Hiom S. J.,
    Validation of disinfection techniques in hospital aseptic dispensing units. The Pharmaceutical Journal 2000, 265, 277– 278.
    OpenUrl
  4. 4.↵
    1. Hiom S. J.,
    2. Lowe C.,
    3. Oldcome M.,
    Development and validation of a method to assess alcohol transfer disinfection procedures. The Pharmaceutical Journal 2004, 272, 611– 614.
    OpenUrl
  5. 5.↵
    1. Curnyn E.,
    Evaluation of Aseptic Transfer Techniques; Survey of Disinfectant Use in Hospital Pharmacy Cleanrooms. MSc Thesis, Aston University, Birmingham, UK, 2005.
  6. 6.↵
    1. McDonnell G.,
    2. Russell A. D.,
    Antiseptics and disinfectants: activity, action and resistance. Clin. Microbiol. Rev. 1999, 12, 147– 179.
    OpenUrlAbstract/FREE Full Text
  7. 7.↵
    1. Russell A. D.,
    Bacterial spores and chemical sporicidal agents. Clin. Microbiol. Rev 1990, 3 ( 2), 99– 119.
    OpenUrlAbstract/FREE Full Text
  8. 8.↵
    1. Russell A. D.,
    Mechanisms of bacterial resistance to biocides. International Biodeterioration and Biodegradation 1995, 36, 247– 265.
    OpenUrl
  9. 9.↵
    1. Richard V.,
    2. Van der Auwera P.,
    3. Snoeck R.,
    4. Daneau D.,
    5. Meunier F.,
    Nosocomial bacteremia caused by Bacillus species. Eur. J. Clin. Microbiol. Infect. Dis 1988, 7 ( 6), 783– 785.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.↵
    1. Medina T. V.,
    2. Herrero C. G. M.,
    3. Curiel A. G.,
    4. Atienza M. F.,
    A microbial growth study in parenteral nutrition. Nutrición Hospitalaria 1989, 4 ( 5), 283– 289.
    OpenUrl
  11. 11.↵
    1. Boom F. A.,
    2. Van der Heijden Van Beek M. A.,
    3. Paalman A. C.,
    4. Stout-Zonneveld A.,
    Microbiological aspects of heat sterilization of drugs. III. Heat resistance of spore-forming bacteria, isolated from large-volume parenterals. Pharmaceutisch Weekblad. Scientific Edition 1991, 13 ( 3), 130– 136 (1991).
    OpenUrlPubMed
  12. 12.↵
    1. Froud G.,
    Reducing risks from everyday items. European Journal of Contamination Control: Cleanroom Technology 2005, 8. http://www.cleanroom-technology.co.uk/story.asp?storyCode=34883 Accessed April 14th 2008.
  13. 13.↵
    1. Bounoure F.,
    2. Fiquet H.,
    3. Arnaud P.,
    Comparison of hydrogen peroxide and peracetic acid as isolator sterilization agents in a hospital pharmacy. American Journal of Health-System Pharmacy 2006, 63 ( 5), 451– 455.
    OpenUrl
  14. 14.↵
    1. Setlow P.,
    Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals. J. Appl. Microbiol 2006, 101 ( 3), 514– 525.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    1. Tennen R.,
    2. Setlow B.,
    3. Dans K. L.,
    4. Loshin C. A.,
    5. Setlow P.,
    Mechanisms of killing spores of Bacillus subtilis by iodine, glutaraldehyde and nitrous acid. J. Appl. Microbiol 2000, 89 ( 2), 330– 338.
    OpenUrlCrossRefPubMed
  16. 16.↵
    1. Loshon C. A.,
    2. Melly E.,
    3. Setlow B.,
    4. Setlow P.,
    Analysis of killing of spores of Bacillus subtilis by a new disinfectant, Sterilox®. J. Appl. Microbiol. 2001, 91, 1051– 1058.
    OpenUrlCrossRefPubMed
  17. 17.↵
    1. Genest P. C.,
    2. Setlow B.,
    3. Melly E.,
    4. Setlow P.,
    Killing of spores of Bacillus subtilis by peroxynitrite appears to be caused by membrane damage. Microbiology 2002, 148, 307– 314.
    OpenUrlAbstract/FREE Full Text
  18. 18.↵
    1. Cortezzo D. E.,
    2. Koziol-Dybe D.,
    3. Setlow B.,
    4. Setlow P.,
    Treatment with oxidizing agents of spores of Bacillus subtilis and sensitizes spores to subsequent stress. J. Appl. Microbiol. 2004, 97, 838– 852.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Setlow B.,
    2. Loshon C. A.,
    3. Genest P. C.,
    4. Cavan A. E.,
    5. Setlow C.,
    6. Setlow P.,
    Mechanisms of killing spores of Bacillus subtilis by acid, alkali and ethanol. J. Appl. Microbiol. 2002, 92, 362– 375.
    OpenUrlCrossRefPubMed
  20. 20.↵
    1. Young S. B.,
    2. Setlow P.,
    Mechanisms of killing of Bacillus subtilis spores by hypochlorite and chlorine dioxide. J. Appl. Microbiol. 2003, 95, 54– 67.
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. Russell A. D.,
    Bacterial resistance to disinfectants: present knowledge and future problems. J. Hosp. Infect 1999, 43 ( Suppl.), S57– S68.
    OpenUrlCrossRefPubMedWeb of Science
  22. 22.↵
    1. Sutton S. V. W.,
    2. Proud D. W.,
    3. Rachui S.,
    4. Brannan D. K.,
    Validation of microbial recovery from disinfectants. PDA J. Pharm. Sci. Technol 2002, 56 ( 5), 255– 266.
    OpenUrlAbstract/FREE Full Text
  23. 23.
    1. Wax R.,
    2. Freese E.,
    Initiation of the germination of Bacillus subtilis spores by a combination of compounds in Place of L-alanine. J. Bacteriol 1968, 95 ( 2), 433– 438.
    OpenUrlAbstract/FREE Full Text
  24. 24.
    1. Cabrera-Martinez R. M.,
    2. Tovar-Rojo F.,
    3. Vepachedu V. R.,
    4. Setlow P.,
    Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis. J. Bacteriol. 2002, 185 ( 8), 2457– 2464.
    OpenUrl
  25. 25.↵
    1. Driks A.,
    From rings to layers: surprising patterns of protein deposition during bacterial spore assembly. J. Bacteriol 2004, 186 ( 14), 4423– 4426.
    OpenUrlFREE Full Text
  26. 26.↵
    1. Bradley D. E.,
    2. Franklin J. G.,
    Electron microscope survey of the surface configuration of spores of the genus Bacillus. J. Bacteriol. 1958, 76 ( 6), 618– 630.
    OpenUrl
  27. 27.↵
    1. Fernando W. J.,
    2. Othman R.,
    Relevance of diffusion through bacterial spore coats/membranes and the associated concentration boundary layers in the initial lag phase of inactivation: a case study for Bacillus subtilis with ozone and monochloramine. Mathematical Biosciences 2006, 199, 175– 187.
    OpenUrlCrossRefPubMed
  28. 28.↵
    1. Melly E.,
    2. Genest P. C.,
    3. Gilmore M. E.,
    4. Little S.,
    5. Popham D. L.,
    6. Driks A.,
    7. Setlow P.,
    Analysis of the properties of Bacillus subtilis prepared at different temperatures. J. Appl. Microbiol. 2002, 92, 1105– 1115.
    OpenUrlCrossRefPubMed
  29. 29.
    1. Setlow B.,
    2. Setlow P.,
    Binding of small, acid-soluble spore proteins to DNA plays a significant role in the resistance of Bacillus subtilis spores to hydrogen peroxide. Appl. Environ. Microbiol. 1993, 59, 3418– 3423.
    OpenUrlAbstract/FREE Full Text
  30. 30.↵
    1. Setlow B.,
    2. Setlow C. A.,
    3. Setlow P.,
    Killing bacterial spores by organic hydroperoxides. Journal of Industrial Microbiology and Biotechnology 1997, 18, 384– 388.
    OpenUrl
  31. 31.↵
    1. Fraise A.,
    2. Lambert P. A.,
    3. Mailard J.-Y.,
    Russell, Hugo & Ayliffe's Principles and Practices of Disinfection, Preservation & Sterilization, 4th ed.; Blackwell Scientific Publications: Oxford, 2004; pp 235– 236.
PreviousNext
Back to top

In This Issue

PDA Journal of Pharmaceutical Science and Technology: 63 (2)
PDA Journal of Pharmaceutical Science and Technology
Vol. 63, Issue 2
March/April 2009
  • Table of Contents
  • Index by Author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on PDA Journal of Pharmaceutical Science and Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Evaluation of Disinfecting Procedures for Aseptic Transfer in Hospital Pharmacy Departments
(Your Name) has sent you a message from PDA Journal of Pharmaceutical Science and Technology
(Your Name) thought you would like to see the PDA Journal of Pharmaceutical Science and Technology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
4 + 8 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Evaluation of Disinfecting Procedures for Aseptic Transfer in Hospital Pharmacy Departments
Manita Mehmi, Lindsay J. Marshall, Peter A. Lambert, Julian C. Smith
PDA Journal of Pharmaceutical Science and Technology Mar 2009, 63 (2) 123-138;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Evaluation of Disinfecting Procedures for Aseptic Transfer in Hospital Pharmacy Departments
Manita Mehmi, Lindsay J. Marshall, Peter A. Lambert, Julian C. Smith
PDA Journal of Pharmaceutical Science and Technology Mar 2009, 63 (2) 123-138;
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgements
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Reducing the risk of non-sterility of aseptic handling in hospital pharmacies, part B: risk control
  • Google Scholar

More in this TOC Section

  • Container Closure Integrity of Vial Primary Packaging Systems under Frozen Storage Conditions: A Case Study
  • Advances in Large Volume Subcutaneous Injections: A Pilot Tolerability Study of an Innovative Needle-Free Injection Platform
  • Quantification and Stability Impact Assessment of Drop Stresses in Biologic Drug Products
Show more Research

Similar Articles

Readers

  • About
  • Table of Content Alerts/Other Alerts
  • Subscriptions
  • Terms of Use
  • Contact Editors

Author/Reviewer Information

  • Author Resources
  • Submit Manuscript
  • Reviewers
  • Contact Editors

Parenteral Drug Association, Inc.

  • About
  • Advertising/Sponsorships
  • Events
  • PDA Bookstore
  • Press Releases

© 2023 PDA Journal of Pharmaceutical Science and Technology ISSN: 1079-7440

Powered by HighWire