Skip to main content

Main menu

  • Home
  • Content
    • Current Issue
    • Past Issues
    • Accepted Articles
    • Email Alerts
    • RSS
    • Terms of Use
  • About PDA JPST
    • JPST Editors and Editorial Board
    • About/Vision/Mission
    • Paper of the Year
  • Author & Reviewer Resources
    • Author Resources / Submit
    • Reviewer Resources
  • JPST Access and Subscriptions
    • PDA Members
    • Institutional Subscriptions
    • Nonmember Access
  • Support
    • Join PDA
    • Contact
    • Feedback
    • Advertising
    • CiteTrack
  • .
    • Visit PDA
    • PDA Letter
    • Technical Reports
    • news uPDATe
    • Bookstore

User menu

  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
PDA Journal of Pharmaceutical Science and Technology
  • .
    • Visit PDA
    • PDA Letter
    • Technical Reports
    • news uPDATe
    • Bookstore
  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart
PDA Journal of Pharmaceutical Science and Technology

Advanced Search

  • Home
  • Content
    • Current Issue
    • Past Issues
    • Accepted Articles
    • Email Alerts
    • RSS
    • Terms of Use
  • About PDA JPST
    • JPST Editors and Editorial Board
    • About/Vision/Mission
    • Paper of the Year
  • Author & Reviewer Resources
    • Author Resources / Submit
    • Reviewer Resources
  • JPST Access and Subscriptions
    • PDA Members
    • Institutional Subscriptions
    • Nonmember Access
  • Support
    • Join PDA
    • Contact
    • Feedback
    • Advertising
    • CiteTrack
  • Follow pda on Twitter
  • Visit PDA on LinkedIn
  • Visit pda on Facebook
Research ArticleResearch

Development of Matrix-Type Transdermal Delivery of Lornoxicam: In Vitro Evaluation and Pharmacodynamic and Pharmacokinetic Studies in Albino Rats

Dheeraj T. Baviskar, Venkatesh B. Parik and Dinesh J. Jain
PDA Journal of Pharmaceutical Science and Technology January 2013, 67 (1) 9-22; DOI: https://doi.org/10.5731/pdajpst.2013.00898
Dheeraj T. Baviskar
1Institute of Pharmaceutical Education, Boradi, Shirpur, Dhule 425428 (M.H.) India and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: baviskar@sancharnet.in
Venkatesh B. Parik
1Institute of Pharmaceutical Education, Boradi, Shirpur, Dhule 425428 (M.H.) India and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dinesh J. Jain
2College of Pharmacy, I.P.S. Academy, Rajendra Nagar, Indore 452012 (M.P.) India
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • References
  • Info & Metrics
  • PDF
Loading

References

  1. 1.↵
    1. Berba J.,
    2. Granson S.,
    3. Langle J.,
    4. Banakar, U. V
    . In vitro release of selected nonsteroidal anti-inflammatory analgesics from reservoir type transdermal formulations. Drug Dev. Ind. Pharm. 1991, 17 (1), 55–65.
    OpenUrl
  2. 2.↵
    1. Beetge E.,
    2. Plessis J.,
    3. Muler, D. G.,
    4. Goosen C.,
    5. Rensburg, F. J
    . The influence of the physicochemical characteristics and pharmacokinetic properties of selected NSAIDs on their transdermal absorption. Int. J. Pharm. 2000, 193 (2), 261–264.
    OpenUrlCrossRefPubMedWeb of Science
  3. 3.↵
    1. Codes G.,
    2. Fischer W.,
    3. Legler U.,
    4. Wolff, H. M
    . Proceedings of 3rd TTS Symposium; Tokyo, Japan, 1987; pp 3–8.
  4. 4.↵
    1. Robinson J. R.,
    2. Lee V. H. L.
    1. Chien Y. W
    . Transdermal Therapeutic System. In Controlled Drug Delivery Fundamentals and applications. 2nd ed.; Robinson J. R., Lee V. H. L. Eds.; Marcel Dekker: New York, 1987; pp 524–552.
  5. 5.↵
    1. Koskelaa, R. V.,
    2. Hirvonen J.,
    3. Monkkonen J.,
    4. Kiesvaara J.,
    5. Antila S.,
    6. Lehtonen L.,
    7. Urtti A
    . Transdermal delivery of levosimendan. Eur. J. Pharm. Sci. 2000, 11 (4), 343–350.
    OpenUrlCrossRefPubMedWeb of Science
  6. 6.↵
    1. Guy, R. H.,
    2. Hadgraft J
    . Physicochemical aspects of percutaneous penetration and its enhancement. Pharm. Res. 1988, 5 (12), 753–758.
    OpenUrlPubMed
  7. 7.↵
    1. Balfour, J. A.,
    2. Fitton A.,
    3. Barradell, L. B
    . Lornoxicam: A review of its pharmacology and therapeutic potential in the management of painful and inflammatory conditions. Drugs 1996, 51 (4), 639–657.
    OpenUrlPubMedWeb of Science
  8. 8.↵
    1. Skjodt, N. M.,
    2. Davies, N. M
    . Clinical pharmacokinetics of lornoxicam: A short half-life oxicam. Clin. Pharmacokinet. 1998, 34 (6), 421–428.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. Baboota S.,
    2. Shakeel F.,
    3. Ahuja A.,
    4. Ali J.,
    5. Shaafiq S
    . Design development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib. Acta Pharm. 2007, 57 (3), 315–332.
    OpenUrlPubMed
  10. 10.↵
    1. Escribano E.,
    2. Calpena, A. C.,
    3. Queralt J.,
    4. Obach R.,
    5. Domenech J
    . Assessment of diclofenac permeation with different formulations: anti-inflammatory study of a selected formula. Eur. J. Pharm. Sci. 2003, 19 (4), 203–210.
    OpenUrlPubMed
  11. 11.↵
    1. Aronson J. K
    . Meyler's Side Effects of Drugs: The International Encyclopedia of adverse drug reactions and Interactions; Elsevier: Amsterdam, The Netherlands, 2006; pp 2167–2168.
  12. 12.↵
    1. Yakhno N.,
    2. Guekht A.,
    3. Skoromets A.,
    4. Spirin N.,
    5. Strachunskaya E.,
    6. Ternavsky A.,
    7. Olsen, K. J.,
    8. Moller, P. L
    . Analgesic efficacy and safety of lornoxicam quick-release formulation compared with diclofenac potassium: randomised, double-blind trial in acute low back pain. Clin. Drug Investig. 2006, 26 (5), 267–277.
    OpenUrlPubMed
  13. 13.↵
    1. Jantharaprapap R.,
    2. Stagni G
    . Effects of penetration enhancers on in vitro permeability of meloxicam gels. Int. J. Pharm. 2007, 343 (1–2), 26–33.
    OpenUrlPubMed
  14. 14.↵
    1. Aqil M.,
    2. Ali A
    . Monolithic matrix type transdermal drug delivery systems of pinacidil monohydrate: in vitro characterization. Eur. J. Pharm. Biopharm. 2002, 54 (2), 161–164.
    OpenUrlPubMed
  15. 15.↵
    1. Pandit V.,
    2. Khanum A.,
    3. Bhaskaran S.,
    4. Banu V
    . Formulation and evaluation of transdermal films for the treatment of overactive bladder. Int. J. Pharm. Tech. Res. 2009, 1 (3), 799–804.
    OpenUrl
  16. 16.↵
    1. Aulton M. E
    . Pharmaceutics: The science of dosage form design, 2nd ed.; Churchill Livingstone: New York, 2002; pp 487–495.
  17. 17.↵
    1. Sumanta M. K.,
    2. Dube R.,
    3. Suresh B
    . Transdermal drug delivery system of a haloperidol to overcome self-induced extrapyramidal syndrome. Drug Dev. Ind. Pharm. 2003, 29 (4), 405–415.
    OpenUrlPubMed
  18. 18.↵
    1. Gattani S. G.,
    2. Gaud R. S.,
    3. Chaturvedi S. C
    . Formulation and evaluation of transdermal films of chlorpheniramine maleate. Indian Drugs 2007, 44, 27–33.
    OpenUrl
  19. 19.↵
    1. Bharkatia M.,
    2. Nema R. K.,
    3. Gupta G. D.,
    4. Gaud R. S
    . Designing and evaluation of propranolol hydrochloride transdermal patch. The Pharma Rev. 2005, 3, 113–116.
    OpenUrl
  20. 20.↵
    1. Stoughton R. B.,
    2. Fritsch W
    . Influence of dimethyl sulfoxide on human percutaneous absorption. Drug Dev. Ind. Pharm. 2003, 29 (4), 405–407.
    OpenUrlPubMed
  21. 21.↵
    1. Gupta P. S.,
    2. Jain S. K
    . Effective and controlled transdermal delivery of metoprololtratarate. Int. Jour. Pharm. Sci. 2005, 67 (3), 346–350.
    OpenUrl
  22. 22.↵
    1. Kulkarni R. V.,
    2. Mutalik S.,
    3. Hiremath D
    . Effect of plasticizers on the permeability and mechanical properties of eudragit films for transdermal application. Int. Jour. Pharm. Sci. 2002, 64 (1), 28–31.
    OpenUrl
  23. 23.↵
    1. Rao R. P.,
    2. Divan P. V
    . Influence of casting solvent on permeability of ethyl cellulose free films for transdermal use. East Pharma. 1997, 40, 135–137.
    OpenUrl
  24. 24.↵
    1. Ramesh G. Y.,
    2. Vishnu V.,
    3. Kishan V.,
    4. Rao Y. M
    . Development of nitrendipine transdermal patches: in vitro and ex vivo characterization. Curr. Drug. Deliv. 2007, 4 (1), 69–76.
    OpenUrlPubMed
  25. 25.↵
    1. Donbrow M.,
    2. Samuelov Y
    . Zero order drug delivery from double-layered porous films: release rate profiles from ethyl cellulose, hydroxypropyl cellulose and polyethylene glycol mixtures. J. Pharm. Pharmacol. 1980, 32 (7), 463–470.
    OpenUrlPubMed
  26. 26.↵
    1. Wagner J. G
    . Interpretation of percent dissolved time plots derived from in vitro testing of conventional tablets and capsules. J. Pharm. Sci. 1969, 58 (10), 1253–1257.
    OpenUrlPubMed
  27. 27.↵
    1. Higuchi T
    . Mechanism of sustained action medication. Theoretical analysis of rate of release of solid drug dispersed in solid matrices. J. Pharm. Sci. 1963, 52 (12), 1145–1149.
    OpenUrlCrossRefPubMedWeb of Science
  28. 28.↵
    1. Singh S
    . Drug stability testing and shelf life determination according to international guidelines. Pharm. Tech. 1999, 23 (6), 68–88.
    OpenUrl
  29. 29.↵
    1. Winter C. A.,
    2. Risley E. A.,
    3. Nuss C. W
    . Carrageen ininduced oedema in hind paw of the rat as an assay for anti-inflammatory drugs. Proc. Soc. Exp. Biol. Med. 1962, 111, 544–547.
    OpenUrlAbstract/FREE Full Text
  30. 30.↵
    1. Baker A. K.,
    2. Hoffmann V. L. H.,
    3. Meert T. F
    . Dextromethorphan and ketamine potentiate the antinociceptive effects of μ- but not delta- or kappa-opioid agonists in a mouse model of acute pain. Pharmacol. Biochem. Behav. 2002, 74, 73–86.
    OpenUrlCrossRefPubMedWeb of Science
  31. 31.↵
    1. Aher K. B.,
    2. Bhavar G. B.,
    3. Joshi H. P
    . Rapid RP-HPLC method for quantitative determination of lornoxicam in bulk and pharmaceutical formulations. Int. J. Chem. Tech. Res. 2011, 3 (3), 1220–1224.
    OpenUrl
  32. 32.↵
    1. Draize J. H.,
    2. Woodward G.,
    3. Calvery H. O
    . Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J. Pharmacol. Exp. Ther. 1944, 82, 377–379.
    OpenUrlFREE Full Text
  33. 33.↵
    1. Mutalik S.,
    2. Udupa N
    . Glibenclamide transdermal patches: physicochemical, pharmacodynamic, and pharmacokinetic evaluations. J. Pharm. Sci. 2004, 93 (6), 1577–1594.
    OpenUrlPubMed
  34. 34.↵
    1. Korsmeyer R. W.,
    2. Gurny R.,
    3. Doelker E.,
    4. Buri P.,
    5. Peppas N. A
    . Mechanisms of solute release from porous hydrophilic polymers. Int. J. Pharm. 1983, 15 (1), 25–35.
    OpenUrlCrossRefWeb of Science
  35. 35.↵
    1. Peppas N. A
    . Pharmaceutical analysis of Fickian and non-Fickian drug release from polymers. ActaHelv. 1985, 60, 110–111.
    OpenUrl
  36. 36.↵
    1. Bodmeir R.,
    2. Paeratakul O
    . Drug release from laminated polymeric films prepared from aqueous latexes. J. Pharm. Sci. 1990, 79 (1), 32–36.
    OpenUrlCrossRefPubMedWeb of Science
PreviousNext
Back to top

In This Issue

PDA Journal of Pharmaceutical Science and Technology: 67 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 67, Issue 1
January/February 2013
  • Table of Contents
  • Index by Author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on PDA Journal of Pharmaceutical Science and Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Development of Matrix-Type Transdermal Delivery of Lornoxicam: In Vitro Evaluation and Pharmacodynamic and Pharmacokinetic Studies in Albino Rats
(Your Name) has sent you a message from PDA Journal of Pharmaceutical Science and Technology
(Your Name) thought you would like to see the PDA Journal of Pharmaceutical Science and Technology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
14 + 1 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Development of Matrix-Type Transdermal Delivery of Lornoxicam: In Vitro Evaluation and Pharmacodynamic and Pharmacokinetic Studies in Albino Rats
Dheeraj T. Baviskar, Venkatesh B. Parik, Dinesh J. Jain
PDA Journal of Pharmaceutical Science and Technology Jan 2013, 67 (1) 9-22; DOI: 10.5731/pdajpst.2013.00898

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Development of Matrix-Type Transdermal Delivery of Lornoxicam: In Vitro Evaluation and Pharmacodynamic and Pharmacokinetic Studies in Albino Rats
Dheeraj T. Baviskar, Venkatesh B. Parik, Dinesh J. Jain
PDA Journal of Pharmaceutical Science and Technology Jan 2013, 67 (1) 9-22; DOI: 10.5731/pdajpst.2013.00898
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • 1. Introduction
    • 2. Materials and Methods
    • 3. Results and Discussion
    • 4. Conclusions
    • Conflict of Interest Statement
    • Acknowledgements
    • References
  • Figures & Data
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • A Holistic Approach for Filling Volume Variability Evaluation and Control with Statistical Tool
  • A Proof-of-Concept Study on a Universal Standard Kit to Evaluate the Risks of Inspectors for Their Foundational Ability of Visual Inspection of Injectable Drug Products
  • Quantitative and Qualitative Evaluation of Microorganism Profile Identified in Bioburden Analysis in a Biopharmaceutical Facility in Brazil: Criteria for Classification and Management of Results
Show more Research

Similar Articles

Keywords

  • Transdermal
  • Lornoxicam
  • In vitro permeation
  • Anti-inflammatory
  • Analgesic
  • Pharmacokinetic
  • Eudragit

Readers

  • About
  • Table of Content Alerts/Other Alerts
  • Subscriptions
  • Terms of Use
  • Contact Editors

Author/Reviewer Information

  • Author Resources
  • Submit Manuscript
  • Reviewers
  • Contact Editors

Parenteral Drug Association, Inc.

  • About
  • Advertising/Sponsorships
  • Events
  • PDA Bookstore
  • Press Releases

© 2025 PDA Journal of Pharmaceutical Science and Technology Print ISSN: 1079-7440  Digital ISSN: 1948-2124

Powered by HighWire