Research ArticleProceedings of the 2013 Viral Clearance Symposium
Viral Inactivation: Low pH and Detergent
Laura Durno and Omar Tounekti
PDA Journal of Pharmaceutical Science and Technology January 2015, 69 (1) 163-172; DOI: https://doi.org/10.5731/pdajpst.2015.01040
Laura Durno
1Health Canada, Biologics and Genetic Therapies Directorate, Centre for the Evaluation of Radiopharmaceuticals and Biotherapeutics, Tunney's Pasture, 100 Eglantine Driveway, Ottawa, Canada, K1A 0K9
Omar Tounekti
1Health Canada, Biologics and Genetic Therapies Directorate, Centre for the Evaluation of Radiopharmaceuticals and Biotherapeutics, Tunney's Pasture, 100 Eglantine Driveway, Ottawa, Canada, K1A 0K9
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In This Issue
PDA Journal of Pharmaceutical Science and Technology
Vol. 69, Issue 1
January/February 2015
Viral Inactivation: Low pH and Detergent
Laura Durno, Omar Tounekti
PDA Journal of Pharmaceutical Science and Technology Jan 2015, 69 (1) 163-172; DOI: 10.5731/pdajpst.2015.01040
Jump to section
- Article
- Introduction
- Virus Inactivation At Low Ph: Impact of Buffers, Ph Value, Protein Concentration, and Temperature On the Inactivation of Retroviruses (Franz Nothelfer, Hans-Georg Bischof, Helmut Winter, Joey Studts, Boehringer Ingelheim Pharma Gmbh & Co. Kg; Alice Marinaci and Horst Ruppach, Charles River Biopharmaceutical Services)
- Method of Inactivating Enveloped Viruses Using Eco-friendly, Cost Effective, Zwitterionic Detergents (Lynn Conley, Biogen Idec)
- Investigation of Alternative and Eco-friendly Detergents for Viral Inactivation (S. Fisher and L. Norling, Genentech)
- XMuLV Inactivation By Triton X-100: Impact of Process Conditions and Points of Use (Shivanthi Chinniah and Lisa Connell-Crowley, Amgen)
- Summary
- References
- Figures & Data
- References
- Info & Metrics
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- Session 1.1: Viral Clearance Using Traditional, Well-Understood Unit Operations: Low pH and Detergent Viral Inactivation