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Research ArticleProceedings of the 2013 Viral Clearance Symposium

Session 1.5: Other Viral Clearance and Inactivation Approaches (Multimodal Chromatography, Membrane Chromatography, Chemical Precipitation)

Brian Hubbard
PDA Journal of Pharmaceutical Science and Technology January 2015, 69 (1) 173-182; DOI: https://doi.org/10.5731/pdajpst.2015.01041
Brian Hubbard
CMC Bioprocess Consulting, LLC, Santa Fe, NM 87506
Ph.D.
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  • For correspondence: brianfromseattlewa@hotmail.com
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Article Information

vol. 69 no. 1 173-182
DOI 
https://doi.org/10.5731/pdajpst.2015.01041
PubMed 
25691725

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online February 17, 2015.

Copyright & Usage 
© PDA, Inc. 2015

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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Viral removal by column chromatography in downstream processing of monoclonal antibodies
    Yifeng Li
    Protein Expression and Purification 2022 198
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PDA Journal of Pharmaceutical Science and Technology: 69 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 69, Issue 1
January/February 2015
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Session 1.5: Other Viral Clearance and Inactivation Approaches (Multimodal Chromatography, Membrane Chromatography, Chemical Precipitation)
Brian Hubbard
PDA Journal of Pharmaceutical Science and Technology Jan 2015, 69 (1) 173-182; DOI: 10.5731/pdajpst.2015.01041

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Session 1.5: Other Viral Clearance and Inactivation Approaches (Multimodal Chromatography, Membrane Chromatography, Chemical Precipitation)
Brian Hubbard
PDA Journal of Pharmaceutical Science and Technology Jan 2015, 69 (1) 173-182; DOI: 10.5731/pdajpst.2015.01041
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  • Article
    • Background
    • Inactivation of Retroviruses by Sodium Caprylate at Neutral pH (Olga Galperina, GSK)
    • Sodium Caprylate Solubility
    • Inactivation Conditions
    • Main Conclusions
    • Achieving Robust Viral Clearance with Mixed-Mode Anion Exchange Chromatography (Mark Teeters, Janssen Pharmaceutical Research and Development)
    • Evolution toward Membrane Chromatography and the Impact upon Virus Reduction (James Berrie, Lonza)
    • Viral Clearance on Ceramic Hydroxyapatite Chromatography (Matthew Dickson, Ph.D., MedImmune)
    • Assessment of High-Temperature/Short-Time Treatment as Viral Barrier for Various Cell Culture Media (John Mattila, Regeneron)
    • Strategies for Effective and Cost-Efficient Viral Clearance Studies To Support Early-Phase Programs (Michael Clark, Ph.D., AbbVie)
    • Summary
    • References
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Cited By...

  • Proceedings of the 2019 Viral Clearance Symposium, Session 2: New Modalities in Chromatography and Adsorptive Filters
  • Session 3.1: Protein A, Hydroxyapatite, and Mixed-Mode Chromatography
  • Session 3.2: Viral Clearance of Emerging Unit Operations: Membrane Chromatography, Other Methods, Etc.
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More in this TOC Section

Proceedings of the 2013 Viral Clearance Symposium

  • Viral Clearance Using Traditional, Well-Understood Unit Operations: Session 1.2. Anion Exchange Chromatography; and Session 1.3. Protein A Chromatography
  • Session 4: Overall Integrated Viral Clearance and Adventitious Agents Strategy
Show more Proceedings of the 2013 Viral Clearance Symposium

Conference Proceeding

  • Viral Clearance Using Traditional, Well-Understood Unit Operations: Session 1.2. Anion Exchange Chromatography; and Session 1.3. Protein A Chromatography
  • Session 4: Overall Integrated Viral Clearance and Adventitious Agents Strategy
  • Proceedings of the 2017 Viral Clearance Symposium, Session 4: Submission Strategies
Show more Conference Proceeding

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