Filling of High-Concentration Monoclonal Antibody Formulations into Pre-filled Syringes: Investigating Formulation-Nozzle Interactions To Minimize Nozzle Clogging

References

1. 1.↵
   1. Shieu W.,
   2. Torhan S.,
   3. Chan E.,
   4. Gikanga B.,
   5. Huubard A.,
   6. Stauch O. B.,
   7. Maa Y.-F.

   Filling of high-concentration monoclonal antibody formulations into pre-filled syringes: filling parameter investigation and optimization. PDA J. Pharm. Sci. Technol. 2014, 68 (2), 153–163.

   OpenUrlAbstract/FREE Full Text
2. 2.↵
   1. Belongia B.,
   2. Blanck R.,
   3. Tingley S.

   Single-use disposable filling for sterile pharmaceuticals. Pharm. Eng. 2013, 23 (3), 1–7.

   OpenUrl
3. 3.↵
   1. Eibl R.,
   2. Eibl D.

   1. Eibl D.,
   2. Peuker T.,
   3. Eibl R.

   Chapter 1. Single-Use Equipment in Biopharmaceutical Manufacture: A Brief Introduction. In Single-Use Technology in Biopharmaceutical Manufacture; Eibl R., Eibl D., Eds.; John Wiley & Sons, Inc.: Hoboken, NJ, 2011; pp 3–11.
4. 4.↵
   1. Xu B.,
   2. Liu D.,
   3. Xu G.,
   4. Zhang X.,
   5. Bi L.

   A measurement method for contact angle based on Hough transformation. Measurement 2013, 46 (3), 1109–1117.

   OpenUrl
5. 5.↵
   1. Clarson S. J.,
   2. Fitzgerald J. J.,
   3. Owen M. J.,
   4. Smith S. D.

   1. She H.,
   2. Chaudhury M. K.,
   3. Owen M. J.

   Surface properties of thin film polydimethylsiloxane. In ACS Symposium Series 729, Silicones and Silicone-Modified Materials; Clarson S. J., Fitzgerald J. J., Owen M. J., Smith S. D., Eds.; American Chemical Society: Washington, DC, 2000; p 322.
6. 6.↵
   1. Colas A.,
   2. Malczewski R.,
   3. Ulman K

   . Silicone tubing for pharmaceutical processing. Dow-Corning Form No. 52-1067-01. 2004. Available at http://www.dowcorning.com/content/publishedlit/52-1067-01.pdf (accessed September 9, 2014).
7. 7.↵
   1. Englander T.,
   2. Wiegel D.,
   3. Naji L.,
   4. Arnold K.

   Dehydration of glass surfaces studied by contact angle measurements. J. Colloid Interface Sci. 1996, 179 (2), 635–636.

   OpenUrlCrossRefWeb of Science
8. 8.↵
   1. Bhandari B. R.,
   2. Datta N.,
   3. Howes T.

   Problems associated with spray drying of sugar-rich foods. Drying Technol. 1997, 15 (2), 671–684.

   OpenUrl
9. 9.↵
   1. Papadakis S. E.,
   2. Bahu R. E.

   Sticky issue of drying. Drying Technol. 1992, 10 (4), 817–837.

   OpenUrl
10. 10.↵
    1. Bowen M.,
    2. Turok R.,
    3. Maa Y.-F.

    Spray drying of monoclonal antibodies: investigating powder-based biologic drug substance bulk storage. Drying Technol. 2013, 31 (13–14), 1441–1450.

    OpenUrl