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Research ArticleTechnology/Application

Rapid Identification and Characterization of Formulated Protein Products by Raman Spectroscopy Coupled with Discriminant Analysis

Xiaolin Cao, Dan Zhou, James A. Loussaert, David S. Meriage, Joseph D. Levine, John P. Gabrielson and Zai-Qing Wen
PDA Journal of Pharmaceutical Science and Technology January 2016, 70 (1) 62-75; DOI: https://doi.org/10.5731/pdajpst.2015.005769
Xiaolin Cao
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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  • For correspondence: xiaolinc@amgen.com
Dan Zhou
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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James A. Loussaert
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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David S. Meriage
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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Joseph D. Levine
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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John P. Gabrielson
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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Zai-Qing Wen
Attribute Sciences, Process Development, Amgen Inc., Thousand Oaks, CA 91320
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PDA Journal of Pharmaceutical Science and Technology: 70 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 70, Issue 1
January/February 2016
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Rapid Identification and Characterization of Formulated Protein Products by Raman Spectroscopy Coupled with Discriminant Analysis
Xiaolin Cao, Dan Zhou, James A. Loussaert, David S. Meriage, Joseph D. Levine, John P. Gabrielson, Zai-Qing Wen
PDA Journal of Pharmaceutical Science and Technology Jan 2016, 70 (1) 62-75; DOI: 10.5731/pdajpst.2015.005769

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Rapid Identification and Characterization of Formulated Protein Products by Raman Spectroscopy Coupled with Discriminant Analysis
Xiaolin Cao, Dan Zhou, James A. Loussaert, David S. Meriage, Joseph D. Levine, John P. Gabrielson, Zai-Qing Wen
PDA Journal of Pharmaceutical Science and Technology Jan 2016, 70 (1) 62-75; DOI: 10.5731/pdajpst.2015.005769
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Keywords

  • Formulated Protein Products
  • Rapid Identification
  • Rapid Characterization
  • Raman spectroscopy
  • Discriminant Analysis
  • Principal component analysis
  • Mahalanobis distance

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