Session 4.2: Viral Spiking, Viral Preparation, and Upstream Risk Mitigation Strategies

References

1. 1.↵
   1. Labrijn A. F.,
   2. Meesters J. I.,
   3. de Goeij B. E.,
   4. van den Bremer E. T.,
   5. Neijssen J.,
   6. van Kampen M. D.,
   7. Strumane K.,
   8. Verploegen S.,
   9. Kundu A.,
   10. Gramer M. J.,
   11. van Berkel P. H.,
   12. van de Winkel J. G.,
   13. Schuurman J.,
   14. Parren P. W.

   Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange. Proc. Natl Acad. Sci. USA 2013, 110 (13), 5145–5150.

   OpenUrlAbstract/FREE Full Text
2. 2.↵
   1. Lutz H.,
   2. Chang W.,
   3. Blandl T.,
   4. Ramsey G.,
   5. Parella J.,
   6. Fisher J.,
   7. Gefroh E.

   Qualification of a novel inline spiking method for virus filter validation. Biotechnol. Prog. 2011, 27 (1), 121–128.

   OpenUrlPubMed
3. 3.↵
   1. Wieser A.,
   2. Berting A.,
   3. Medek C.,
   4. Poelsler G.,
   5. Kreil T. R.

   The evolution of down-scale virus filtration equipment for virus clearance studies. Biotechnol. Bioeng. 2015, 112 (3), 633–637.

   OpenUrl
4. 4.↵
   1. Victoria J. G.,
   2. Wang C.,
   3. Jones M. S.,
   4. Jaing C.,
   5. McLoughlin K.,
   6. Gardner S.,
   7. Delwart E. L.

   Viral nucleic acids in live-attenuated vaccines: detection of minority variants and an adventitious virus. J. Virol. 2010, 84 (12), 6033–6040.

   OpenUrlAbstract/FREE Full Text
5. 5.↵
   1. Ma H.,
   2. Galvin T. A.,
   3. Glasner D. R.,
   4. Shaheduzzaman S.,
   5. Khan A. S.

   Identification of a novel rhabdovirus in Spodoptera frugiperda cell lines. J. Virol. 2014, 88 (12), 6576–6585.

   OpenUrlAbstract/FREE Full Text