A Comparison of Protein Stability in Prefillable Syringes Made of Glass and Plastic

Lloyd Waxman; Vinod D. Vilivalam

doi:10.5731/pdajpst.2016.007146

Research ArticleResearch

A Comparison of Protein Stability in Prefillable Syringes Made of Glass and Plastic

Lloyd Waxman and Vinod D. Vilivalam

PDA Journal of Pharmaceutical Science and Technology November 2017, 71 (6) 462-477; DOI: https://doi.org/10.5731/pdajpst.2016.007146

Lloyd Waxman

West Pharmaceutical Services, Exton, PA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: Lloyd.Waxman@westpharma.com

Vinod D. Vilivalam

West Pharmaceutical Services, Exton, PA

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
References
Info & Metrics
PDF

Article Information

vol. 71 no. 6 462-477

DOI

https://doi.org/10.5731/pdajpst.2016.007146

PubMed

28819049

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online December 9, 2017.

Article Versions

previous version (August 17, 2017 - 18:10).
You are viewing the most recent version of this article.

Author Information

Lloyd Waxman* and
Vinod D. Vilivalam

West Pharmaceutical Services, Exton, PA

↵* Corresponding Author: West Pharmaceutical Services, 530 Herman O. West Drive, Exton, PA 19341. Telephone: (610) 594-3495; e-mail: Lloyd.Waxman@westpharma.com

View Full Text

Cited By...

15 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Protein aggregation – Mechanisms, detection, and control

Wei Wang, Christopher J. Roberts

International Journal of Pharmaceutics 2018 550 1-2
Science and art of protein formulation development

Wei Wang, Satoshi Ohtake

International Journal of Pharmaceutics 2019 568
Critical analysis of techniques and materials used in devices, syringes, and needles used for intravitreal injections

Gustavo Barreto Melo, Natasha Ferreira Santos da Cruz, Geoffrey Guy Emerson, Flávio Atanázio Rezende, Carsten H. Meyer, Susumu Uchiyama, John Carpenter, Hélio Francisco Shiroma, Michel Eid Farah, Maurício Maia, Eduardo Büchele Rodrigues

Progress in Retinal and Eye Research 2021 80
Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

Alexandre Goyon, Szabolcs Fekete, Alain Beck, Jean-Luc Veuthey, Davy Guillarme

Journal of Chromatography B 2018 1092
Sweeping of Adsorbed Therapeutic Protein on Prefillable Syringes Promotes Micron Aggregate Generation

Takahiro Maruno, Hiroki Watanabe, Saki Yoneda, Takayuki Uchihashi, Satoru Adachi, Kunihito Arai, Taichi Sawaguchi, Susumu Uchiyama

Journal of Pharmaceutical Sciences 2018 107 6
Impact of succussion on pharmaceutical preparations analyzed by means of patterns from evaporated droplets

Maria Olga Kokornaczyk, Sandra Würtenberger, Stephan Baumgartner

Scientific Reports 2020 10 1
Characterization of Aggregated Antibody-Silicone Oil Complexes: From Perspectives of Morphology, 3D Image, and Fcγ Receptor Activation

Masato Kiyoshi, Minoru Tada, Hiroko Shibata, Michihiko Aoyama, Akiko Ishii-Watabe

Journal of Pharmaceutical Sciences 2021 110 3
Prefilled dual chamber devices (DCDs) – Promising high-quality and convenient drug delivery system

Rahul G. Ingle, Wei-Jie Fang

International Journal of Pharmaceutics 2021 597
Application of Formulation Principles to Stability Issues Encountered During Processing, Manufacturing, and Storage of Drug Substance and Drug Product Protein Therapeutics

Samadhi Vitharana, Joshua M. Stillahn, Derrick S. Katayama, Charles S. Henry, Mark Cornell Manning

Journal of Pharmaceutical Sciences 2023 112 11
Impact of Post Manufacturing Handling of Protein-Based Biologic Drugs on Product Quality and User Centricity

Elia Cappelletto, Stanley C. Kwok, Léa Sorret, Nathalie Fuentes, Annette M. Medina, Stephen Burleigh, Jonas Fast, Isla S. Mackenzie, Anna Millqvist Fureby, Mattias Paulsson, Marie Wahlgren, Ulla Elofsson, Angela Flynn, Giorgia Miolo, Lina Nyström, Patrizia Polverino De Laureto, Giorgia De Paoli

Journal of Pharmaceutical Sciences 2024 113 8
Evaluation of a novel silicone oil free primary packaging system with PTFE-based barrier stopper for biologics

Fabian Moll, Karoline Bechtold-Peters, Wolfgang Friess

European Journal of Pharmaceutics and Biopharmaceutics 2023 190
Protein Instability at Interfaces During Drug Product Development

Coleman Vaclaw, Valerie Pringle, Aishik Chakraborty, Prajnaparamita Dhar

2021 43
Ophthalmic Product Development

Gitanjali Sharma, Chen Zhou, Saurabh Wadhwa, Ashwin C. Parenky, Kenneth S. Graham, Amardeep S. Bhalla, Dingjiang Liu, Hunter H. Chen, Mohammed Shameem

2021 37
Research on Gliding and Discharge Performance of Suspended Injection from Syringe —Effect of Diameter Ratio of Suspending Particle against Needle Hole on Needle Passageability—

Toshiyuki Niwa, Megumi Morisaki, Keita Kondo, Atsushi Nakashima

YAKUGAKU ZASSHI 2020 140 5
Impact of protein adsorption during biopharmaceutical manufacture & storage

John D. Downey, Abina M. Crean, Katie B. Ryan

European Journal of Pharmaceutical Sciences 2025 209

PreviousNext

In This Issue

PDA Journal of Pharmaceutical Science and Technology

Vol. 71, Issue 6

November/December 2017

Table of Contents
Index by Author

Download PDF

Article Alerts

Email Article

Citation Tools

A Comparison of Protein Stability in Prefillable Syringes Made of Glass and Plastic

Lloyd Waxman, Vinod D. Vilivalam

PDA Journal of Pharmaceutical Science and Technology Nov 2017, 71 (6) 462-477; DOI: 10.5731/pdajpst.2016.007146

Share This Article:

Tweet Widget

Jump to section

Article
Figures & Data
References
Info & Metrics
PDF

No related articles found.

PubMed
Google Scholar

Cited By...

Risk Mitigation of Drug Shortages--A New Concept for Vials Designed to Improve Fill and Finish Performance
Holistic Extractables and Leachables Program: Evaluations of Prefilled Syringe Systems for Biotechnology Products

Google Scholar

Keywords

prefillable syringe
Silicone oil
Tungsten
Crystal Zenith
CZ
protein aggregation
biotherapeutic protein
Protein stability

Main menu

User menu

Search

A Comparison of Protein Stability in Prefillable Syringes Made of Glass and Plastic

Article Information

Article Versions

Author Information

Cited By...

In This Issue

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

Readers

Author/Reviewer Information

Parenteral Drug Association, Inc.

Citation Manager Formats

Main menu

User menu

Search

A Comparison of Protein Stability in Prefillable Syringes Made of Glass and Plastic

Article Information

Article Versions

Author Information

Cited By...

In This Issue

Jump to section

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

Readers

Author/Reviewer Information

Parenteral Drug Association, Inc.

We use cookies on this site to enhance your user experience