Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

doi:10.5731/pdajpst.2017.008086

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology November 2017, 71 (6) 478-487; DOI: https://doi.org/10.5731/pdajpst.2017.008086

Masakazu Tsuchiya

Charles River, Microbial Solutions

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For correspondence: Kaz.Tsuchiya@crl.com

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vol. 71 no. 6 478-487

DOI

https://doi.org/10.5731/pdajpst.2017.008086

PubMed

28928294

Published By

Parenteral Drug Association (PDA)

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1079-7440

Online ISSN

1948-2124

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Published online December 9, 2017.

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Masakazu Tsuchiya*

Charles River, Microbial Solutions

↵* Corresponding Author: Charles River, 1023 Wappoo Road, Suite 43B, Charleston, SC 29407. Telephone +1-843-402-4900; e-mail: Kaz.Tsuchiya{at}crl.com

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology Nov 2017, 71 (6) 478-487; DOI: 10.5731/pdajpst.2017.008086

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology Nov 2017, 71 (6) 478-487; DOI: 10.5731/pdajpst.2017.008086

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Keywords

Lipopolysaccharide
Reference Standard Endotoxin
Low Endotoxin Recovery
Limulus amebocyte lysate
Bacterial endotoxins test
Naturally Occurring Endotoxin

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