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Research ArticleProceedings of the 2017 Viral Clearance Symposium

Proceedings of the 2017 Viral Clearance Symposium, Session 6: Ensuring Viral Safety in Continuous Processing

Sarah A. Johnson and David Roush
PDA Journal of Pharmaceutical Science and Technology September 2018, 72 (5) 516-524; DOI: https://doi.org/10.5731/pdajpst.2018.009183
Sarah A. Johnson
1Center for Drug Evaluation and Research, Office of Biotechnology Products, U.S. Food and Drug Administration, Silver Spring, MD; and
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  • For correspondence: sarah.johnson1@fda.hhs.gov
David Roush
2Bioprocess Development/Biologics Research, Merck & Co., Inc., Kenilworth, NJ, USA
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Reference

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    1. Chinniah S.,
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    Design, construction, and optimization of a novel, modular, and scalable incubation chamber for continuous viral inactivation. Biotechnol Prog 2017, 33 (4), 954–965.
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    1. Parker S. A.,
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    Design of a novel continuous flow reactor for low pH viral inactivation. Biotechnol Prog 2017, 33, 954–965.
    OpenUrl
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In This Issue

PDA Journal of Pharmaceutical Science and Technology: 72 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 72, Issue 5
September/October 2018
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Proceedings of the 2017 Viral Clearance Symposium, Session 6: Ensuring Viral Safety in Continuous Processing
Sarah A. Johnson, David Roush
PDA Journal of Pharmaceutical Science and Technology Sep 2018, 72 (5) 516-524; DOI: 10.5731/pdajpst.2018.009183

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Proceedings of the 2017 Viral Clearance Symposium, Session 6: Ensuring Viral Safety in Continuous Processing
Sarah A. Johnson, David Roush
PDA Journal of Pharmaceutical Science and Technology Sep 2018, 72 (5) 516-524; DOI: 10.5731/pdajpst.2018.009183
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  • Article
    • Abstract
    • Session Background and Overview
    • Participants' Contributions
    • Viral Clearance for Continuous Viral Inactivation
    • Alternative Strategies for Viral Validation of a Continuous Viral Filtration Step
    • Next Steps
    • Disclaimer
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More in this TOC Section

Proceedings of the 2017 Viral Clearance Symposium

  • Proceedings of the 2017 Viral Clearance Symposium, Session 4: Submission Strategies
  • Proceedings of the 2017 Viral Clearance Symposium: Conclusion
  • Proceedings of the 2017 Viral Clearance Symposium, Session 1.2: Upstream Mitigation, Part 2—Virus Barrier Filter and HTST
Show more Proceedings of the 2017 Viral Clearance Symposium

Conference Proceeding

  • Proceedings of the 2017 Viral Clearance Symposium, Session 4: Submission Strategies
  • Proceedings of the 2017 Viral Clearance Symposium: Conclusion
  • Proceedings of the 2017 Viral Clearance Symposium, Session 1.2: Upstream Mitigation, Part 2—Virus Barrier Filter and HTST
Show more Conference Proceeding

Similar Articles

Keywords

  • Viral clearance
  • Continuous processing
  • Small-scale model
  • Chromatography
  • Virus inactivation
  • Virus-spiking strategy

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