Split-Cakes, Still Delicious

Philippe Lam; Thomas W. Patapoff

doi:10.5731/pdajpst.2018.008813

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Split-Cakes, Still Delicious

Philippe Lam and Thomas W. Patapoff

PDA Journal of Pharmaceutical Science and Technology January 2019, 73 (1) 16-29; DOI: https://doi.org/10.5731/pdajpst.2018.008813

Philippe Lam

1Pharmaceutical Processing and Technology Development, Genentech, Inc.; and

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For correspondence: lam.philippe@gene.com

Thomas W. Patapoff

2Early Stage Pharmaceutical Development, Genentech, Inc.

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vol. 73 no. 1 16-29

DOI

https://doi.org/10.5731/pdajpst.2018.008813

PubMed

30158240

Published By

Parenteral Drug Association (PDA)

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1079-7440

Online ISSN

1948-2124

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Published online February 1, 2019.

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previous version (August 29, 2018 - 07:12).
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Philippe Lam1,* and
Thomas W. Patapoff2

¹Pharmaceutical Processing and Technology Development, Genentech, Inc.; and
²Early Stage Pharmaceutical Development, Genentech, Inc.

↵* Corresponding Author: Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA. E-mail: lam.philippe{at}gene.com

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Split-Cakes, Still Delicious

Philippe Lam, Thomas W. Patapoff

PDA Journal of Pharmaceutical Science and Technology Jan 2019, 73 (1) 16-29; DOI: 10.5731/pdajpst.2018.008813

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Split-Cakes, Still Delicious

Philippe Lam, Thomas W. Patapoff

PDA Journal of Pharmaceutical Science and Technology Jan 2019, 73 (1) 16-29; DOI: 10.5731/pdajpst.2018.008813

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Keywords

Lyophilization
cake structure
spherulitic ice crystal
lamellar ice crystal
Split-cake

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