Article Figures & Data
Figures
- Figure 1
Pressure ranges used for integrity science studies.
- Figure 2
Test setup (A) and test sample (B) for microbial ingress testing.
- Figure 3
Test setup (A) and test sample (B) for liquid leakage testing.
- Figure 4
Test setup for flow rate measurement.
- Figure 5
Probability curves for microbial ingress in polyethylene film; (A) 0 mbar, (B) 70 mbar, (C) 150 mbar, and (D) 300 mbar.
- Figure 6
Experimental data and models comparing microbial ingress and liquid leakage; (A) ethylene vinyl acetate film and (B) polyethylene film.
Tables
Pressure (Mbar) 0 70 150 300 EVA (300 µm) 288 45 45 150 PE (400 µm) 288 194 45 150 Total 1205 EVA, ethylene vinyl acetate; PE, polyethylene.
Pressure 0 70 150 300 Film Type EVA PE EVA PE EVA PE EVA PE Nominal defect size [µm] Bacterial Ingress/Total Samples 1 0/7 0/2 0/1 0/5 0/30 0/30 2 0/18 0/18 0/8 0/2 0/2 0/6 0/30 2/30 3 1/6* 0/1 0/2 2/4 8/30 2/30 4 0/1 0/3 1/5 5 0/1 0/34 0/4 2/4 17/30 10/30 6 0/2 1/3 7 0/1 1/1 1/1 8 2/3 2/6 1/3 9 0/2 10 0/30 0/30 0/1 1/31 1/5 0/2 12 1/1 13 1/1 15 0/30 0/30 1/1 30/31 1/2 3/4 16 1/1 17 1/1 20 0/30 1/30* 0/1 31/31 2/3 1/1 25 0/30 0/30 1/1 31/31 1/1 30 0/30 0/30 1/1 1/1 2/2 3/3 35 1/1 40 1/30 0/30 1/1 1/1 2/2 3/3 50 1/30 6/30 1/1 4/4 3/3 4/4 60 3/3 3/3 2/2 1/1 70 3/3 1/1 1/1 75 1/1 80 14/30 15/30 2/2 1/1 90 3/3 1/1 1/1 100 14/30 22/30 1/1 1/1 1/1 110 1/1 1/1 120 1/1 1/1 130 1/1 150 1/1 EVA, ethylene vinyl acetate; PE, polyethylene.
EVA Film Pressure (mbar) Defect Size (µm) 0 56.62 70 3.62 150 4.18 300 2.00 PE Film 0 45.87 70 9.78 150 1.96 300 2.83 EVA, ethylene vinyl acetate; PE, polyethylene
Pressure (Mbar) 70 150 300 Model Solution Water TSB Water TSB Water TSB EVA (300 µm) 6 6 - 6 6 6 EVA (360 µm) 6 6 3 12 6 6 PE (400 µm) 18 15 - 3 15 15 Total 135 EVA, ethylene vinyl acetate; PE, polyethylene; TSB, tryptic soy broth.
- TABLE V
Liquid Leakages vs Total Number of Test Samples per Film Type, Model Solution, and Test Pressure
Model Solution Water TSB Applied Pressure (Mbar) Nominal Defect Size (µm) No. of Leaking Samples /No. of Tested Samples No. of Leaking Samples /No. of Tested Samples EVA 300 µm EVA 360 µm PE 400 µm EVA 300 µm EVA 360 µm PE 400 µm 300 10 3/3 3/3 5/6 3/3 5 3/3 0/3 4/6 3 3/3 3/3 6/6 2 0/3 0/3 0/3 0/3 0/3 150 10 5 0/3 6/12 3 1/3 2 0/3 0/3 70 25 3/3 3/3 20 3/3 15 3/3 3/3 10 3/3 3/3 3/3 2/3 1/3 3/3 5 3/3 3/3 3 0/3 2 0/3 0/3 0/3 0/3 0/3 EVA, ethylene vinyl acetate; PE, polyethylene; TSB, tryptic soy broth.
