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Characterization of Protein Aggregating Tungstates: Electrospray Mass Spectrometry Analysis of Extracts from Pre-filled Syringes and from Tungsten Pins Used in the Manufacture of Syringes

Michael Ronk, Hans Lee, Kiyoshi Fujimori, Ping Yeh and Yasser Nashed-Samuel
PDA Journal of Pharmaceutical Science and Technology January 2016, pdajpst.2015.005546; DOI: https://doi.org/10.5731/pdajpst.2015.005546
Michael Ronk
1 Amgen, Inc.;
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  • For correspondence: mronk@amgen.com
Hans Lee
2 Amgen, Inc
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Kiyoshi Fujimori
2 Amgen, Inc
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Ping Yeh
2 Amgen, Inc
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Yasser Nashed-Samuel
1 Amgen, Inc.;
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Article Information

pdajpst.2015.005546
DOI 
https://doi.org/10.5731/pdajpst.2015.005546
PubMed 
26797967

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Received March 27, 2015
  • Accepted October 9, 2015
  • Published online January 21, 2016.

Article Versions

  • You are currently viewing a previous version of this article (January 21, 2016 - 17:53).
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Copyright & Usage 
Copyright © 2016, Parenteral Drug Association

Author Information

  1. Michael Ronk1,3 (mronk{at}amgen.com),
  2. Hans Lee2 (hansl{at}amgen.com),
  3. Kiyoshi Fujimori2 (kiyoshif{at}amgen.com),
  4. Ping Yeh2 (pyeh{at}amgen.com) and
  5. Yasser Nashed-Samuel1 (snashed{at}amgen.com)
  1. 1 Amgen, Inc.;
  2. 2 Amgen, Inc
  1. ↵* Corresponding author; email: mronk{at}amgen.com

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PDA Journal of Pharmaceutical Science and Technology: 79 (2)
PDA Journal of Pharmaceutical Science and Technology
Vol. 79, Issue 2
March/April 2025
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Characterization of Protein Aggregating Tungstates: Electrospray Mass Spectrometry Analysis of Extracts from Pre-filled Syringes and from Tungsten Pins Used in the Manufacture of Syringes
Michael Ronk, Hans Lee, Kiyoshi Fujimori, Ping Yeh, Yasser Nashed-Samuel
PDA Journal of Pharmaceutical Science and Technology Jan 2016, pdajpst.2015.005546; DOI: 10.5731/pdajpst.2015.005546

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Characterization of Protein Aggregating Tungstates: Electrospray Mass Spectrometry Analysis of Extracts from Pre-filled Syringes and from Tungsten Pins Used in the Manufacture of Syringes
Michael Ronk, Hans Lee, Kiyoshi Fujimori, Ping Yeh, Yasser Nashed-Samuel
PDA Journal of Pharmaceutical Science and Technology Jan 2016, pdajpst.2015.005546; DOI: 10.5731/pdajpst.2015.005546
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Keywords

  • Mass spectrometry
  • protein aggregation
  • Syringe Extracts
  • Tungstate
  • Tungsten
  • Tungsten Pins

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