Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

doi:10.5731/pdajpst.2017.008086

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology September 2017, pdajpst.2017.008086; DOI: https://doi.org/10.5731/pdajpst.2017.008086

Masakazu Tsuchiya

Charles River Laboratories

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For correspondence: kaz.tsuchiya@crl.com

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pdajpst.2017.008086

DOI

https://doi.org/10.5731/pdajpst.2017.008086

PubMed

28928294

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Received June 14, 2017
Accepted August 29, 2017
Published online September 19, 2017.

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Masakazu Tsuchiya 1 (kaz.tsuchiya{at}crl.com) (http://www.criver.com/)

Charles River Laboratories

↵* Corresponding author; email: kaz.tsuchiya{at}crl.com

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology Sep 2017, pdajpst.2017.008086; DOI: 10.5731/pdajpst.2017.008086

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Factors Affecting Reduction of Reference Endotoxin Standard Activity Caused by Chelating Agent/Detergent Matrices: Kinetic Analysis of Low Endotoxin Recovery

Masakazu Tsuchiya

PDA Journal of Pharmaceutical Science and Technology Sep 2017, pdajpst.2017.008086; DOI: 10.5731/pdajpst.2017.008086

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Keywords

Bacterial endotoxins test
Limulus amebocyte lysate
Lipopolysaccharide
Low Endotoxin Recovery
Naturally Occurring Endotoxin
Reference Standard Endotoxin

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