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Application of enzyme indicators in hydrogen peroxide biodecontamination cycle development: A critical evaluation of indicator variability and correlation to biological indicator results

Andreas Schachtschneider, Stephanie Klein and Kate Marshall
PDA Journal of Pharmaceutical Science and Technology June 2021, pdajpst.2020.012294; DOI: https://doi.org/10.5731/pdajpst.2020.012294
Andreas Schachtschneider
1 Metall+Plastic GmbH, Radolfzell, Germany;
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  • For correspondence: andreas.schachtschneider@metall-plastic.de
Stephanie Klein
2 OPTIMA pharma GmbH, Schwaebisch Hall, Germany;
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  • For correspondence: stephanie.klein@optima-packaging.com
Kate Marshall
3 Protak Scientific Ltd, Redhill, United Kingdom
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  • For correspondence: kate.marshall@protakscientific.com
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Article Information

pdajpst.2020.012294
DOI 
https://doi.org/10.5731/pdajpst.2020.012294
PubMed 
34131011

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Received August 20, 2020
  • Accepted June 9, 2021
  • Published online June 15, 2021.

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  • You are currently viewing a previous version of this article (June 15, 2021 - 08:06).
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Copyright & Usage 
Copyright © 2021, Parenteral Drug Association

Author Information

  1. Andreas Schachtschneider1,4 (andreas.schachtschneider{at}metall-plastic.de) (https://www.metall-plastic.com/en),
  2. Stephanie Klein2 (stephanie.klein{at}optima-packaging.com) (https://www.optima-packaging.com/en/pharma) and
  3. Kate Marshall3 (kate.marshall{at}protakscientific.com) (https://www.protakscientific.com/)
  1. 1 Metall+Plastic GmbH, Radolfzell, Germany;
  2. 2 OPTIMA pharma GmbH, Schwaebisch Hall, Germany;
  3. 3 Protak Scientific Ltd, Redhill, United Kingdom
  1. ↵* Corresponding author; email: andreas.schachtschneider{at}metall-plastic.de

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PDA Journal of Pharmaceutical Science and Technology: 77 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 77, Issue 1
January/February 2023
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Application of enzyme indicators in hydrogen peroxide biodecontamination cycle development: A critical evaluation of indicator variability and correlation to biological indicator results
Andreas Schachtschneider, Stephanie Klein, Kate Marshall
PDA Journal of Pharmaceutical Science and Technology Jun 2021, pdajpst.2020.012294; DOI: 10.5731/pdajpst.2020.012294

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Application of enzyme indicators in hydrogen peroxide biodecontamination cycle development: A critical evaluation of indicator variability and correlation to biological indicator results
Andreas Schachtschneider, Stephanie Klein, Kate Marshall
PDA Journal of Pharmaceutical Science and Technology Jun 2021, pdajpst.2020.012294; DOI: 10.5731/pdajpst.2020.012294
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Keywords

  • Decontamination cycle development
  • Enzyme indicator
  • Geobacillus stearothermophilus
  • Hydrogen peroxide
  • Isolator validation
  • Thermostable adenylate kinase (tAK)

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