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An investigation into the spatial distribution of moisture in freeze-dried products using NIR spectroscopy and chemical imaging

AZHERUDDIN MOHAMMED, ANTOINE COURNOYER and RYAN GOSSELIN
PDA Journal of Pharmaceutical Science and Technology September 2022, pdajpst.2020.012443; DOI: https://doi.org/10.5731/pdajpst.2020.012443
AZHERUDDIN MOHAMMED
1 UNIVERSITE DE SHERBROOKE;
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  • For correspondence: moha1503@usherbrooke.ca
ANTOINE COURNOYER
2 Pfizer Inc
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  • For correspondence: antoine.cournoyer@pfizer.com
RYAN GOSSELIN
1 UNIVERSITE DE SHERBROOKE;
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  • For correspondence: ryan.gosselin@usherbrooke.ca
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Article Information

pdajpst.2020.012443
DOI 
https://doi.org/10.5731/pdajpst.2020.012443
PubMed 
36122914

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Received October 20, 2020
  • Accepted August 26, 2022
  • Published online September 19, 2022.

Copyright & Usage 
Copyright © 2022, Parenteral Drug Association

Author Information

  1. AZHERUDDIN MOHAMMED1,3 (moha1503{at}usherbrooke.ca),
  2. ANTOINE COURNOYER2 (antoine.cournoyer{at}pfizer.com) and
  3. RYAN GOSSELIN1 (ryan.gosselin{at}usherbrooke.ca) (https://www.usherbrooke.ca/gchimiquebiotech/departement/professeurs/ryan-gosselin/)
  1. 1 UNIVERSITE DE SHERBROOKE;
  2. 2 Pfizer Inc
  1. ↵* Corresponding author; email: moha1503{at}usherbrooke.ca

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PDA Journal of Pharmaceutical Science and Technology: 77 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 77, Issue 1
January/February 2023
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An investigation into the spatial distribution of moisture in freeze-dried products using NIR spectroscopy and chemical imaging
AZHERUDDIN MOHAMMED, ANTOINE COURNOYER, RYAN GOSSELIN
PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2020.012443; DOI: 10.5731/pdajpst.2020.012443

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An investigation into the spatial distribution of moisture in freeze-dried products using NIR spectroscopy and chemical imaging
AZHERUDDIN MOHAMMED, ANTOINE COURNOYER, RYAN GOSSELIN
PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2020.012443; DOI: 10.5731/pdajpst.2020.012443
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Keywords

  • Chemometrics
  • Freeze-drying
  • NIR
  • NIR Imaging
  • PAT
  • Spatial moisture variations

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