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OtherResearch Paper

Coring and fragmentation of elastomeric needle shield in a pre-filled syringe

Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi and Guangli Hu
PDA Journal of Pharmaceutical Science and Technology April 2025, pdajpst.2024-003041; DOI: https://doi.org/10.5731/pdajpst.2024-003041.1
Sahab Babaee
1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA
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  • For correspondence: sahab.babaee@merck.com guangli.hu@merck.com
Sean Teller
2Veryst Engineering LLC, Needham, MA 02494, USA
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Kavin Kowsari
1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA
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Nikolaos Vasios
2Veryst Engineering LLC, Needham, MA 02494, USA
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Steven C. Persak
1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA
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Nagi Elabbasi
2Veryst Engineering LLC, Needham, MA 02494, USA
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Guangli Hu
1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065, USA
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  • For correspondence: guangli.hu@merck.com sahab.babaee@merck.com
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PDA Journal of Pharmaceutical Science and Technology: 79 (3)
PDA Journal of Pharmaceutical Science and Technology
Vol. 79, Issue 3
May/June 2025
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Coring and fragmentation of elastomeric needle shield in a pre-filled syringe
Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi, Guangli Hu
PDA Journal of Pharmaceutical Science and Technology Apr 2025, pdajpst.2024-003041; DOI: 10.5731/pdajpst.2024-003041.1
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Keywords

  • Prefilled syringe
  • Rigid needle shield
  • Coring
  • Elastomer material
  • Numerical modeling

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© 2025 PDA Journal of Pharmaceutical Science and Technology Print ISSN: 1079-7440  Digital ISSN: 1948-2124

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Coring and fragmentation of elastomeric needle shield in a pre-filled syringe
Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi, Guangli Hu
PDA Journal of Pharmaceutical Science and Technology Apr 2025, pdajpst.2024-003041; DOI: 10.5731/pdajpst.2024-003041.1

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