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Research ArticleTECHNOLOGY/APPLICATION

Practical Application of the Cake-Complete, Pore-Plugging Model for Sizing Normal Flow Filters

Jonathan T. Royce
PDA Journal of Pharmaceutical Science and Technology September 2009, 63 (5) 462-471;
Jonathan T. Royce
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References

  1. ↵
    1. Van Reis R.,
    2. Zydney A.
    Membrane separations in biotechnology. Current Opinion in Biotechnology 2001, 12 (2), 208–211.
    OpenUrlCrossRefPubMed
  2. ↵
    1. Sharma A.,
    2. Anderson S.,
    3. Rathore A.
    Filter clogging issues in sterile filtration. BioPharm International, 2008, 21 (4), 53–57.
    OpenUrl
  3. ↵
    1. Badmington F.,
    2. Honig E.,
    3. Payne M.,
    4. Wilkins R.
    Vmax testing for practical microfiltration train scale-up in biopharmaceutical processing. Pharmaceutical Technology 1995, 19 (9), 48–52.
    OpenUrl
  4. ↵
    1. Van Reis R.,
    2. Zydney A.
    Bioprocess membrane technology. Journal of Membrane Science 2007, 297 (1–2), 16–50.
    OpenUrl
  5. ↵
    1. Zydney A.,
    2. Ho C.
    Scale-up of microfiltration systems: fouling phenomena and vmax analysis. Desalination 2002, 146, 75–81.
    OpenUrl
  6. ↵
    1. Hermia J.
    Constant pressure blocking filtration laws—application to power-law non-newtonian fluids. Chemical Engineering Research and Design 1982, 60, 183–187.
    OpenUrl
  7. ↵
    1. Bolton G.,
    2. LaCasse D.,
    3. Kuriyel R.
    Combined models of membrane fouling: development and application to microfiltration and ultrafiltration of biological fluids. Journal of Membrane Science 2006, 277 (1–2), 75–84.
    OpenUrl
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PDA Journal of Pharmaceutical Science and Technology: 63 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 63, Issue 5
September/October 2009
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Practical Application of the Cake-Complete, Pore-Plugging Model for Sizing Normal Flow Filters
Jonathan T. Royce
PDA Journal of Pharmaceutical Science and Technology Sep 2009, 63 (5) 462-471;

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Practical Application of the Cake-Complete, Pore-Plugging Model for Sizing Normal Flow Filters
Jonathan T. Royce
PDA Journal of Pharmaceutical Science and Technology Sep 2009, 63 (5) 462-471;
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Jump to section

  • Article
    • Abstract
    • Introduction
    • Overview of the Cake-Complete Model
    • Application of the Cake-Complete Model to Constant Pressure Data Estimate of Capacity
    • Initial Estimate of the Initial Flux (J0)
    • Initial Estimate of the Complete Blocking Constant (Kb)
    • Initial Estimate of the Caking Constant (Kc)
    • Optimization and Bounding of Fitted Parameters
    • Solving for Filter Area Requirements
    • Application of the Cake-Complete Model to Constant Flow Data Estimate of Capacity
    • Calculation of Flux (J0)
    • Initial Estimate of the Initial Pressure Drop (P0)
    • Initial Estimates of the Complete Blocking Constant and Caking Constant (Kb and Kc)
    • Optimization and Bounding of Fitted Parameters
    • Solving for Filter Area Requirements
    • Conclusions
    • References
  • Figures & Data
  • Info & Metrics
  • References
  • PDF

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