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PubMed
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History
- Published online January 4, 2012.
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© PDA, Inc. 2011
Author Information
- Jens-Peter Gregersen*
- Technology Development/Viral Safety, Novartis Vaccines, Novartis Vaccines and Diagnostics GmbH, Marburg, Germany
- ↵* Correspondence address: Dr. Jens-Peter Gregersen, Novartis Vaccines and Diagnostics GmbH, 35041 Marburg, Germany. Telephone: 0049 6421 39 2265. E-mail: jens-peter.gregersen{at}novartis.com.
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- Article
- Abstract
- Introduction
- Conventional Test Schemes for Extraneous Viruses
- Detectability of Viruses by Conventional Tests
- Unspecific Side Effects and Questionable Results
- Animal Numbers Needed
- Time and Cost of Conventional Testing
- Neutralization of the Virus Contained in Seed Lots and Virus Harvests
- Applicability of Conventional Tests for Rapidly Changing Viral Seeds
- Conclusions on Conventional Test Regimes
- Alternative Methods and Strategies
- Conflict of Interest Statement
- Acknowledgments
- References
- Figures & Data
- References
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