Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer

Elham Khodaverdi; Arsalan Akbari; Farnaz Sadat Mirzazadeh Tekie; Seyed Ahmad Mohajeri; Gholamhossein Zohuri; Farzin Hadizadeh

doi:10.5731/pdajpst.2013.00908

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Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer

Elham Khodaverdi, Arsalan Akbari, Farnaz Sadat Mirzazadeh Tekie, Seyed Ahmad Mohajeri, Gholamhossein Zohuri and Farzin Hadizadeh

PDA Journal of Pharmaceutical Science and Technology March 2013, 67 (2) 135-145; DOI: https://doi.org/10.5731/pdajpst.2013.00908

Elham Khodaverdi

1Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

3Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

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Arsalan Akbari

1Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

3Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

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Farnaz Sadat Mirzazadeh Tekie

5Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

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Seyed Ahmad Mohajeri

1Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

3Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

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Gholamhossein Zohuri

4Department of Chemistry, Faculty of Science, Ferdowsi University, Mashhad, Iran; and

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Farzin Hadizadeh

2Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;

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For correspondence: hadizadehf@mums.ac.ir

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vol. 67 no. 2 135-145

DOI

https://doi.org/10.5731/pdajpst.2013.00908

PubMed

23569074

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online April 8, 2013.

Author Information

Elham Khodaverdi1,3,
Arsalan Akbari1,3,
Farnaz Sadat Mirzazadeh Tekie5,
Seyed Ahmad Mohajeri1,3,
Gholamhossein Zohuri4 and
Farzin Hadizadeh2,*

¹Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;
²Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;
³Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran;
⁴Department of Chemistry, Faculty of Science, Ferdowsi University, Mashhad, Iran; and
⁵Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

↵* Correspondence author: Farzin Hadizadeh, Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. hadizadehf{at}mums.ac.ir

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Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer

Elham Khodaverdi, Arsalan Akbari, Farnaz Sadat Mirzazadeh Tekie, Seyed Ahmad Mohajeri, Gholamhossein Zohuri, Farzin Hadizadeh

PDA Journal of Pharmaceutical Science and Technology Mar 2013, 67 (2) 135-145; DOI: 10.5731/pdajpst.2013.00908

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Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer

Elham Khodaverdi, Arsalan Akbari, Farnaz Sadat Mirzazadeh Tekie, Seyed Ahmad Mohajeri, Gholamhossein Zohuri, Farzin Hadizadeh

PDA Journal of Pharmaceutical Science and Technology Mar 2013, 67 (2) 135-145; DOI: 10.5731/pdajpst.2013.00908

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Keywords

Tri-block copolymer
PCL-PEG-PCL
Vancomycin
Amphotericin B
In situ forming gel
Drug release
Microwave

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Sustained Delivery of Amphotericin B and Vancomycin Hydrochloride by an Injectable Thermogelling Tri-Block Copolymer

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