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Research ArticleConference Proceeding - Article

Viral Clearance by Traditional Operations With Significant Knowledge Gaps (Session II): Cation Exchange Chromatography (CEX) and Detergent Inactivation

George Miesegaes
PDA Journal of Pharmaceutical Science and Technology January 2014, 68 (1) 30-37; DOI: https://doi.org/10.5731/pdajpst.2014.00964
George Miesegaes
Center for Drug Evaluation and Research (CDER), U.S. Food and Drug Administration (FDA)
Ph.D.
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Article Information

vol. 68 no. 1 30-37
DOI 
https://doi.org/10.5731/pdajpst.2014.00964
PubMed 
24504234

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online February 6, 2014.

Copyright & Usage 
© PDA, Inc. 2014

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PDA Journal of Pharmaceutical Science and Technology: 68 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 68, Issue 1
January/February 2014
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Viral Clearance by Traditional Operations With Significant Knowledge Gaps (Session II): Cation Exchange Chromatography (CEX) and Detergent Inactivation
George Miesegaes
PDA Journal of Pharmaceutical Science and Technology Jan 2014, 68 (1) 30-37; DOI: 10.5731/pdajpst.2014.00964

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Viral Clearance by Traditional Operations With Significant Knowledge Gaps (Session II): Cation Exchange Chromatography (CEX) and Detergent Inactivation
George Miesegaes
PDA Journal of Pharmaceutical Science and Technology Jan 2014, 68 (1) 30-37; DOI: 10.5731/pdajpst.2014.00964
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Jump to section

  • Article
    • CEX Background
    • MuLV Removal by CEX Chromatography (Lisa Connell-Crowley, Amgen)
    • Evaluation of CEX as a Capture Step for mAb Purification (G. Miesegaes, CDER/FDA)
    • Detergent Inactivation Background
    • Virus Inactivation by Detergents (L. Norling; Genentech, a Member of the Roche Group)
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Cited By...

  • Proceedings of the 2019 Viral Clearance Symposium, Session 2: New Modalities in Chromatography and Adsorptive Filters
  • Viral Inactivation: Low pH and Detergent
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More in this TOC Section

  • Emerging Unit Operations (Session III): Hydroxyapatite, Mixed-Mode, and Adsorptive Membrane Chromatography; UV-C Inactivation; Chemical Precipitation
  • Viral Clearance Using Traditional, Well-Understood Unit Operations (Session I): Virus-Retentive Filtration
  • Viral Clearance Integration (Session IV): General Trends, Bracketing, QbD, Virus Preparation Quality Attributes
Show more Conference Proceeding - Article

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