Viral Clearance by Traditional Operations With Significant Knowledge Gaps (Session II): Cation Exchange Chromatography (CEX) and Detergent Inactivation

References

1. 1.↵
   1. Miesegaes G.,
   2. Bailey M.,
   3. Willkommen H.,
   4. Chen Q.,
   5. Roush D.,
   6. Blümel J.,
   7. Brorson K.

   Proceedings of the 2009 Viral Clearance Symposium. Dev. Biol. (Basel) 2010, 133, 3–101.

   OpenUrlPubMedGoogle Scholar
2. 2.↵
   1. Connell-Crowley L.,
   2. Nguyen T.,
   3. Bach J.,
   4. Chinniah S.,
   5. Bashiri H.,
   6. Gillespie R.,
   7. Moscariello J.,
   8. Hinckley P.,
   9. Dehghani H.,
   10. Vunnum S.,
   11. Vedantham G.

   Cation exchange chromatography provides effective retrovirus clearance for antibody purification processes. Biotechnol. Bioeng. 2012, 109 (1), 157–165.

   OpenUrlPubMedGoogle Scholar
3. 3.↵
   1. Miesegaes G.,
   2. Lute S.,
   3. Brorson K.

   Analysis of viral clearance unit operations from monoclonal antibody regulatory submissions. Biotechnol. Bioeng. 2010, 106 (2), 238–246.

   OpenUrlPubMedGoogle Scholar
4. 4.↵
   1. Miesegaes G. R.,
   2. Lute S.,
   3. Strauss D. M.,
   4. Read E. K.,
   5. Venkiteshwaran A.,
   6. Kreuzman A.,
   7. Shah R.,
   8. Shamlou P.,
   9. Chen D.,
   10. Brorson K.

   Monoclonal antibody capture and viral clearance by cation exchange chromatography. Biotechnol. Bioeng. 2012, 109 (8), 2048–2058.

   OpenUrlPubMedGoogle Scholar