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Research ArticleResearch

Parallelism in Practice: Approaches to Parallelism in Bioassays

Kelly Fleetwood, Francis Bursa and Ann Yellowlees
PDA Journal of Pharmaceutical Science and Technology March 2015, 69 (2) 248-263; DOI: https://doi.org/10.5731/pdajpst.2015.01016
Kelly Fleetwood
Quantics Consulting, Edinburgh, United Kingdom
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Francis Bursa
Quantics Consulting, Edinburgh, United Kingdom
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  • For correspondence: francis.bursa@quantics.co.uk
Ann Yellowlees
Quantics Consulting, Edinburgh, United Kingdom
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Article Information

vol. 69 no. 2 248-263
DOI 
https://doi.org/10.5731/pdajpst.2015.01016
PubMed 
25868991

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online April 13, 2015.

Copyright & Usage 
© PDA, Inc. 2015

Author Information

  1. Kelly Fleetwood,
  2. Francis Bursa* and
  3. Ann Yellowlees
  1. Quantics Consulting, Edinburgh, United Kingdom
  1. ↵*Corresponding Author. Telephone: +44 (0) 131 4402781; e-mail: francis.bursa{at}quantics.co.uk
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PDA Journal of Pharmaceutical Science and Technology: 69 (2)
PDA Journal of Pharmaceutical Science and Technology
Vol. 69, Issue 2
March/April 2015
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Parallelism in Practice: Approaches to Parallelism in Bioassays
Kelly Fleetwood, Francis Bursa, Ann Yellowlees
PDA Journal of Pharmaceutical Science and Technology Mar 2015, 69 (2) 248-263; DOI: 10.5731/pdajpst.2015.01016

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Parallelism in Practice: Approaches to Parallelism in Bioassays
Kelly Fleetwood, Francis Bursa, Ann Yellowlees
PDA Journal of Pharmaceutical Science and Technology Mar 2015, 69 (2) 248-263; DOI: 10.5731/pdajpst.2015.01016
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  • Article
    • Abstract
    • 1. Introduction
    • 2. Models for Bioassay Data
    • 3. Three Tests for Parallelism
    • 4. Comparison of Tests Under Different Variance Patterns
    • 5. Parallelism Testing On Simulated Data Sets
    • 6. Comparing the Approaches
    • 7. Discussion
    • 8. Conclusions
    • Conflict of Interest Declaration
    • References
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Keywords

  • Bioassay
  • Parallelism
  • Similarity
  • Equivalence
  • Significance

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