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Research ArticleTechnology/Application

Plasma Decontamination: A Case Study on Kill Efficacy of Geobacillus stearothermophilus Spores on Different Carrier Materials

Egmont Semmler, Wenzel Novak, Wilf Allinson, Darren Wallis, Nigel Wood, Peter Awakowicz and Joachim Wunderlich
PDA Journal of Pharmaceutical Science and Technology May 2016, 70 (3) 256-271; DOI: https://doi.org/10.5731/pdajpst.2015.006163
Egmont Semmler
1Groninger & Co. GmbH, Crailsheim, Germany;
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  • For correspondence: e.semmler@groninger.de
Wenzel Novak
1Groninger & Co. GmbH, Crailsheim, Germany;
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Wilf Allinson
2GlaxoSmithKline plc., Barnard Castle, County Durham, United Kingdom;
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Darren Wallis
2GlaxoSmithKline plc., Barnard Castle, County Durham, United Kingdom;
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Nigel Wood
2GlaxoSmithKline plc., Barnard Castle, County Durham, United Kingdom;
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Peter Awakowicz
3Ruhr-University Bochum, Institute for Plasma Technology, Bochum, Germany;
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Joachim Wunderlich
4Fraunhofer Institute for Process Engineering and Packaging, Freising, Germany
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Article Information

vol. 70 no. 3 256-271
DOI 
https://doi.org/10.5731/pdajpst.2015.006163
PubMed 
27020647

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online May 31, 2016.

Article Versions

  • previous version (March 28, 2016 - 17:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© PDA, Inc. 2016

Author Information

  1. Egmont Semmler1⇑,
  2. Wenzel Novak1,
  3. Wilf Allinson2,
  4. Darren Wallis2,
  5. Nigel Wood2,
  6. Peter Awakowicz3 and
  7. Joachim Wunderlich4
  1. 1Groninger & Co. GmbH, Crailsheim, Germany;
  2. 2GlaxoSmithKline plc., Barnard Castle, County Durham, United Kingdom;
  3. 3Ruhr-University Bochum, Institute for Plasma Technology, Bochum, Germany;
  4. 4Fraunhofer Institute for Process Engineering and Packaging, Freising, Germany
  1. 1 Corresponding Author: Egmont Semmler, Groninger & Co GmbH, Hofaeckerstrasse 9, 74564 Crailsheim, Germany; Telephone: +49 (0)7951/495–3154; e-mail: e.semmler{at}groninger.de
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PDA Journal of Pharmaceutical Science and Technology: 70 (3)
PDA Journal of Pharmaceutical Science and Technology
Vol. 70, Issue 3
May/June 2016
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Plasma Decontamination: A Case Study on Kill Efficacy of Geobacillus stearothermophilus Spores on Different Carrier Materials
Egmont Semmler, Wenzel Novak, Wilf Allinson, Darren Wallis, Nigel Wood, Peter Awakowicz, Joachim Wunderlich
PDA Journal of Pharmaceutical Science and Technology May 2016, 70 (3) 256-271; DOI: 10.5731/pdajpst.2015.006163

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Plasma Decontamination: A Case Study on Kill Efficacy of Geobacillus stearothermophilus Spores on Different Carrier Materials
Egmont Semmler, Wenzel Novak, Wilf Allinson, Darren Wallis, Nigel Wood, Peter Awakowicz, Joachim Wunderlich
PDA Journal of Pharmaceutical Science and Technology May 2016, 70 (3) 256-271; DOI: 10.5731/pdajpst.2015.006163
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  • Article
    • Abstract
    • 1 Introduction
    • 2 Gaseous Plasma Decontamination
    • 3 Reference Setup and Homogeniety of the Gaseous Plasma Decontamination
    • 4 Materials and Methods
    • 5 Results and Discussion
    • 6 Proposal for a (RE-)Validation Scheme
    • Conflict of Interest Declaration
    • Acknowledgements
    • References
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Keywords

  • Plasma decontamination
  • Geobacillus stearothermophilus
  • D-Value
  • Limited Holcomb-Spearman-Karber procedure
  • Resistance
  • Spores
  • Validation
  • Microbiology
  • Surface treatment

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