Characterizing the Overall Derivatization of Conjugated Oligomeric Proteins

References

1. 1.↵
   1. Roberts M. J.,
   2. Bentley M. D.,
   3. Harris J. M.

   Chemistry for Peptide and Protein PEGylation. Adv. Drug Deliv. Rev. 2002, 54 (4), 459–476.

   OpenUrlCrossRefPubMedWeb of Science
2. 2.↵
   1. Pasut G.,
   2. Veronese F. M.

   State of the Art in PEGylation: The Great Versatility Achieved after Forty Years of Research. J. Controlled Release 2012, 161 (2), 461–472.

   OpenUrlCrossRefPubMedWeb of Science
3. 3.↵
   1. Hakem I. F.,
   2. Leech A. M.,
   3. Johnson J. D.,
   4. Donahue S. J.,
   5. Walker J. P.,
   6. Bockstaller M. R.

   Understanding Ligand Distributions in Modified Particle and Particlelike Systems. J. Am. Chem. Soc. 2010, 132 (46), 16593–16598.

   OpenUrlPubMed
4. 4.↵
   1. Hakem I. F.,
   2. Leech A. M.,
   3. Bohn J.,
   4. Walker J. P.,
   5. Bockstaller M. R.

   Analysis of Heterogeneity in Nonspecific PEGylation Reactions of Biomolecules. Biopolymers 2012, 99 (7), 427–435.

   OpenUrl
5. 5.↵
   1. Mullen D. G.,
   2. Fang M.,
   3. Desai A.,
   4. Baker J. R. Jr..,
   5. Orr B. G.,
   6. Banaszak Holl M. M.

   A Quantitative Assessment of Nanoparticle-Ligand Distributions: Implications for Targeted Drug and Imaging Delivery in Dendrimer Conjugates. ACS Nano 2010, 4 (2), 657–670.

   OpenUrlPubMed
6. 6.↵
   1. Aslam M.,
   2. Dent A.

   1. Dent A. H.,
   2. Aslam M.

   The Characterisation of Protein Conjugates. In Bioconjugation: Protein Coupling Techniques for the Biomedical Sciences; Aslam M., Dent A., Eds.; Macmillan Reference Ltd: London, UK, 1999; pp 665–734.
7. 7.↵
   1. Cheng T. L.,
   2. Chuang K. H.,
   3. Chen B. M.,
   4. Roffler S. R.

   Analytical Measurement of PEGylated Molecules. Bioconjugate Chem. 2012, 23 (5), 881–899.

   OpenUrlCrossRefPubMed
8. 8.↵
   1. Fee C. J.,
   2. Van Alstine J. M.

   PEG-proteins: Reaction Engineering and Separation Issues. Chemical Engineering Science 2006, 61 (3), 924–939.

   OpenUrl
9. 9.↵
   1. Janson J. C.

   1. Fee C. J.,
   2. Van Alstine J. M.

   Purification of Pegylated Proteins. In Protein Purification: Principles, High Resolution Methods, and Applications, Janson J. C., Ed.; John Wiley & Sons: Hoboken, NJ, 2011; pp 339–362.
10. 10.↵
    1. Pabst T. M.,
    2. Buckley J. J.,
    3. Ramasubramanyan N.,
    4. Hunter A. K.

    Comparison of Strong Anion-Exchangers for the Purification of a PEGylated Protein. J. Chromatogr., A 2007, 1147 (2), 172–182.

    OpenUrl
11. 11.↵
    1. Box G.,
    2. Behnken D.

    Some New Three Level Designs for the Study of Quantitative Variables. Technometrics 1960, 2 (4), 455–475.

    OpenUrlCrossRef
12. 12.↵
    1. Abuchowski A.,
    2. McCoy J. R.,
    3. Palczuk N. C.,
    4. Van Es T.,
    5. Davis F. F.

    Effect of Covalent Attachment of Polyethylene Glycol on Immunogenicity and Circulating Life of Bovine Liver Catalase. J. Biol. Chem. 1977, 252 (11), 3582–3586.

    OpenUrlAbstract/FREE Full Text
13. 13.↵
    1. Jevsevar S.,
    2. Kunstelj M.,
    3. Porekar V. G.

    PEGylation of Therapeutic Proteins. Biotechnol J. 2010, 5 (1), 113–128.

    OpenUrlCrossRefPubMedWeb of Science
14. 14.↵
    1. Veronese F. M.,
    2. Mero A.

    The Impact of PEGylation on Biological Therapies. BioDrugs 2008, 22 (5), 315–329.

    OpenUrlCrossRefPubMedWeb of Science