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Article CommentaryCommentary

Biocompute Objects—A Step towards Evaluation and Validation of Biomedical Scientific Computations

Vahan Simonyan, Jeremy Goecks and Raja Mazumder
PDA Journal of Pharmaceutical Science and Technology March 2017, 71 (2) 136-146; DOI: https://doi.org/10.5731/pdajpst.2016.006734
Vahan Simonyan
1Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA;
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  • For correspondence: vahan.simonyan@fda.hhs.gov jgoecks@gwu.edu mazumder@gwu.edu
Jeremy Goecks
2Computational Biology Institute, George Washington University, Ashburn, VA, USA; and
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  • For correspondence: vahan.simonyan@fda.hhs.gov jgoecks@gwu.edu mazumder@gwu.edu
Raja Mazumder
3Department of Biochemistry and Molecular Medicine, George Washington University, Washington, DC, USA
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  • For correspondence: vahan.simonyan@fda.hhs.gov jgoecks@gwu.edu mazumder@gwu.edu
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Article Information

vol. 71 no. 2 136-146
DOI 
https://doi.org/10.5731/pdajpst.2016.006734
PubMed 
27974626

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online April 10, 2017.

Article Versions

  • previous version (December 14, 2016 - 05:03).
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Copyright & Usage 
© PDA, Inc. 2017

Author Information

  1. Vahan Simonyan1,*,
  2. Jeremy Goecks2,* and
  3. Raja Mazumder3,*
  1. 1Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA;
  2. 2Computational Biology Institute, George Washington University, Ashburn, VA, USA; and
  3. 3Department of Biochemistry and Molecular Medicine, George Washington University, Washington, DC, USA
  1. ↵* Corresponding Authors: E-mail addresses: Vahan Simonyan: vahan.simonyan{at}fda.hhs.gov; Jeremy Goecks: jgoecks{at}gwu.edu; and Raja Mazumder: mazumder{at}gwu.edu
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PDA Journal of Pharmaceutical Science and Technology: 71 (2)
PDA Journal of Pharmaceutical Science and Technology
Vol. 71, Issue 2
March/April 2017
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Biocompute Objects—A Step towards Evaluation and Validation of Biomedical Scientific Computations
Vahan Simonyan, Jeremy Goecks, Raja Mazumder
PDA Journal of Pharmaceutical Science and Technology Mar 2017, 71 (2) 136-146; DOI: 10.5731/pdajpst.2016.006734

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Biocompute Objects—A Step towards Evaluation and Validation of Biomedical Scientific Computations
Vahan Simonyan, Jeremy Goecks, Raja Mazumder
PDA Journal of Pharmaceutical Science and Technology Mar 2017, 71 (2) 136-146; DOI: 10.5731/pdajpst.2016.006734
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  • Article
    • Abstract
    • Background
    • Experimental Method
    • Experimental Protocol
    • Experimental Instance
    • Biocompute Object (Experimental Instance)
    • Biocompute Template (Experimental Protocol) and Template Library
    • Validation Schema
    • Biocompute Database
    • Utility and Evolving Perspective
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Keywords

  • Biocompute object
  • NGS standardization
  • Computation reproducibility
  • Regulatory research
  • FDA

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