Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes

Viviane Loosli; Oliver Germershaus; Henrik Steinberg; Sascha Dreher; Ulla Grauschopf; Stefanie Funke

doi:10.5731/pdajpst.2017.007997

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Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes

Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf and Stefanie Funke

PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: https://doi.org/10.5731/pdajpst.2017.007997

Viviane Loosli

1Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Institut für Pharma Technology, 4132 Muttenz, Switzerland; and

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Oliver Germershaus

1Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Institut für Pharma Technology, 4132 Muttenz, Switzerland; and

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Henrik Steinberg

2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland

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Sascha Dreher

2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland

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Ulla Grauschopf

2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland

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Stefanie Funke

2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland

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For correspondence: stefanie.funke@roche.com

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vol. 72 no. 3 278-297

DOI

https://doi.org/10.5731/pdajpst.2017.007997

PubMed

29343617

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online June 18, 2018.

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previous version (January 17, 2018 - 16:46).
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Author Information

Viviane Loosli1,
Oliver Germershaus1,
Henrik Steinberg2,
Sascha Dreher2,
Ulla Grauschopf2 and
Stefanie Funke2,*

¹Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Institut für Pharma Technology, 4132 Muttenz, Switzerland; and
²F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland

↵* Corresponding Author: Stefanie Funke, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, CH-4070 Basel, Switzerland. Telephone: +41 61 68 70574; e-mail: stefanie.funke{at}roche.com

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Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes

Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf, Stefanie Funke

PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: 10.5731/pdajpst.2017.007997

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Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes

Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf, Stefanie Funke

PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: 10.5731/pdajpst.2017.007997

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Keywords

functionality
interferometry
3D-Laser Scanning Microscopy
silicone oil layer thickness and distribution
spray-on siliconization
Syringe

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