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Research ArticleResearch

Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes

Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf and Stefanie Funke
PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: https://doi.org/10.5731/pdajpst.2017.007997
Viviane Loosli
1Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Institut für Pharma Technology, 4132 Muttenz, Switzerland; and
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Oliver Germershaus
1Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Institut für Pharma Technology, 4132 Muttenz, Switzerland; and
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Henrik Steinberg
2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland
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Sascha Dreher
2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland
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Ulla Grauschopf
2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland
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Stefanie Funke
2F. Hoffmann-La Roche Ltd, Device Development, PTD Biologics Europe (PTDE-D), 4070 Basel, Switzerland
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  • For correspondence: stefanie.funke@roche.com
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PDA Journal of Pharmaceutical Science and Technology: 72 (3)
PDA Journal of Pharmaceutical Science and Technology
Vol. 72, Issue 3
May/June 2018
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Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes
Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf, Stefanie Funke
PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: 10.5731/pdajpst.2017.007997

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Methods To Determine the Silicone Oil Layer Thickness in Sprayed-On Siliconized Syringes
Viviane Loosli, Oliver Germershaus, Henrik Steinberg, Sascha Dreher, Ulla Grauschopf, Stefanie Funke
PDA Journal of Pharmaceutical Science and Technology May 2018, 72 (3) 278-297; DOI: 10.5731/pdajpst.2017.007997
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Keywords

  • functionality
  • interferometry
  • 3D-Laser Scanning Microscopy
  • silicone oil layer thickness and distribution
  • spray-on siliconization
  • Syringe

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