Table of Contents

July/August 2019; Volume 73,Issue 4

A

  1. Alayli, Sara

    1. Measurement of Equilibration Time of Dry Goods Loads in Autoclaves
      Soham Shah, Sara Alayli and Yiming Peng
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 293-319; DOI: https://doi.org/10.5731/pdajpst.2018.009225

B

  1. Beaugard, Matt

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  2. Berry, Clifford

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  3. Bjerregaard, Lene

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  4. Bradley, Scott

    1. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems—Part 2
      Laura M. Doyle (Drbohlav), Anant Navanithan Sharma, Ganapathy Gopalrathnam, Lihua Huang and Scott Bradley
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 320-330; DOI: https://doi.org/10.5731/pdajpst.2018.009639

  5. Burdick, Richard

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  6. Buscke, Florence

    1. Comparative Leachable Study of Glass Vials to Demonstrate the Impact of Low Fill Volume
      Bernhard Hladik, Florence Buscke, Robert Frost and Uwe Rothhaar
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 345-355; DOI: https://doi.org/10.5731/pdajpst.2018.009472

C

  1. Choi, Daeseok

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  2. Chung, Jee

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  3. Chviruk, Brian

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  4. Coffman, Christine

    1. Enabling Robust and Rapid Raw Material Identification and Release by Handheld Raman Spectroscopy
      Thomas E. Matthews, Christine Coffman, Dave Kolwyck, Dan Hill and Jason E. Dickens
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 356-372; DOI: https://doi.org/10.5731/pdajpst.2018.009563

D

  1. Depatie, Chantal

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  2. Dickens, Jason E.

    1. Enabling Robust and Rapid Raw Material Identification and Release by Handheld Raman Spectroscopy
      Thomas E. Matthews, Christine Coffman, Dave Kolwyck, Dan Hill and Jason E. Dickens
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 356-372; DOI: https://doi.org/10.5731/pdajpst.2018.009563

  3. Downey, Christopher

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  4. Doyle (Drbohlav), Laura M.

    1. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems—Part 2
      Laura M. Doyle (Drbohlav), Anant Navanithan Sharma, Ganapathy Gopalrathnam, Lihua Huang and Scott Bradley
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 320-330; DOI: https://doi.org/10.5731/pdajpst.2018.009639

F

  1. Frost, Robert

    1. Comparative Leachable Study of Glass Vials to Demonstrate the Impact of Low Fill Volume
      Bernhard Hladik, Florence Buscke, Robert Frost and Uwe Rothhaar
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 345-355; DOI: https://doi.org/10.5731/pdajpst.2018.009472

G

  1. Gopalrathnam, Ganapathy

    1. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems—Part 2
      Laura M. Doyle (Drbohlav), Anant Navanithan Sharma, Ganapathy Gopalrathnam, Lihua Huang and Scott Bradley
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 320-330; DOI: https://doi.org/10.5731/pdajpst.2018.009639

  2. Greene, Anne

    1. Quality Risk Management Competency Model—Case for the Need for QRM Competencies
      Ghada Haddad and Anne Greene
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 331-344; DOI: https://doi.org/10.5731/pdajpst.2019.009944

H

  1. Haddad, Ghada

    1. Quality Risk Management Competency Model—Case for the Need for QRM Competencies
      Ghada Haddad and Anne Greene
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 331-344; DOI: https://doi.org/10.5731/pdajpst.2019.009944

  2. Hernandez, Danny

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  3. Herwig, Christoph

    1. Provable Data Integrity in the Pharmaceutical Industry Based on Version Control Systems and the Blockchain
      Valentin Steinwandter and Christoph Herwig
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 373-390; DOI: https://doi.org/10.5731/pdajpst.2018.009407

  4. Hill, Dan

    1. Enabling Robust and Rapid Raw Material Identification and Release by Handheld Raman Spectroscopy
      Thomas E. Matthews, Christine Coffman, Dave Kolwyck, Dan Hill and Jason E. Dickens
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 356-372; DOI: https://doi.org/10.5731/pdajpst.2018.009563

  5. Hladik, Bernhard

    1. Comparative Leachable Study of Glass Vials to Demonstrate the Impact of Low Fill Volume
      Bernhard Hladik, Florence Buscke, Robert Frost and Uwe Rothhaar
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 345-355; DOI: https://doi.org/10.5731/pdajpst.2018.009472

  6. Huang, Lihua

    1. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems—Part 2
      Laura M. Doyle (Drbohlav), Anant Navanithan Sharma, Ganapathy Gopalrathnam, Lihua Huang and Scott Bradley
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 320-330; DOI: https://doi.org/10.5731/pdajpst.2018.009639

I

  1. Ingram, Bev

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

K

  1. Kolwyck, Dave

    1. Enabling Robust and Rapid Raw Material Identification and Release by Handheld Raman Spectroscopy
      Thomas E. Matthews, Christine Coffman, Dave Kolwyck, Dan Hill and Jason E. Dickens
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 356-372; DOI: https://doi.org/10.5731/pdajpst.2018.009563

  2. Krause, Stephan

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

L

  1. Lacana, Emanuela

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  2. Levy, Richard

    1. Editor's Note
      Richard Levy
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 292; DOI: https://doi.org/10.5731/pdajpst.2019.001114

M

  1. Matthews, Thomas E.

    1. Enabling Robust and Rapid Raw Material Identification and Release by Handheld Raman Spectroscopy
      Thomas E. Matthews, Christine Coffman, Dave Kolwyck, Dan Hill and Jason E. Dickens
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 356-372; DOI: https://doi.org/10.5731/pdajpst.2018.009563

P

  1. Peng, Yiming

    1. Measurement of Equilibration Time of Dry Goods Loads in Autoclaves
      Soham Shah, Sara Alayli and Yiming Peng
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 293-319; DOI: https://doi.org/10.5731/pdajpst.2018.009225

  2. Polizzotto, Joe

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

  3. Polozova, Alla

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  4. Purbrick, Daan

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

R

  1. Rellahan, Barbara

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  2. Rothhaar, Uwe

    1. Comparative Leachable Study of Glass Vials to Demonstrate the Impact of Low Fill Volume
      Bernhard Hladik, Florence Buscke, Robert Frost and Uwe Rothhaar
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 345-355; DOI: https://doi.org/10.5731/pdajpst.2018.009472

S

  1. Shacter, Emily

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  2. Shah, Soham

    1. Measurement of Equilibration Time of Dry Goods Loads in Autoclaves
      Soham Shah, Sara Alayli and Yiming Peng
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 293-319; DOI: https://doi.org/10.5731/pdajpst.2018.009225

  3. Shapiro, Marjorie

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  4. Sharma, Anant Navanithan

    1. A Mechanistic Understanding of Polysorbate 80 Oxidation in Histidine and Citrate Buffer Systems—Part 2
      Laura M. Doyle (Drbohlav), Anant Navanithan Sharma, Ganapathy Gopalrathnam, Lihua Huang and Scott Bradley
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 320-330; DOI: https://doi.org/10.5731/pdajpst.2018.009639

  5. Srebalus-Barnes, Catherine

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  6. Stangler, Thomas

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

  7. Steinwandter, Valentin

    1. Provable Data Integrity in the Pharmaceutical Industry Based on Version Control Systems and the Blockchain
      Valentin Steinwandter and Christoph Herwig
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 373-390; DOI: https://doi.org/10.5731/pdajpst.2018.009407

  8. Stevens, Kelly B.

    1. What Does It Really Look Like to Properly Address a “Human Error Problem” in Biopharma? The Human Performance Blue-Sky Description That Will Help Improve Industry Performance
      Clifford Berry, Brian Chviruk, Danny Hernandez, Matt Beaugard, Kelly B. Stevens, Joe Polizzotto, Lene Bjerregaard and Daan Purbrick
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 391-400; DOI: https://doi.org/10.5731/pdajpst.2018.009621

V

  1. Van Der Plas, Martijn

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

W

  1. Welch, Joel

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215

Z

  1. Zhou, Qing

    1. PDA Biosimilars Workshop Report (September 27—28, 2018)—Getting It Right the First Time for Biosimilar Marketing Applications
      Stephan Krause, Emanuela Lacana, Joel Welch, Marjorie Shapiro, Christopher Downey, Jee Chung, Qing Zhou, Martijn Van Der Plas, Chantal Depatie, Bev Ingram, Catherine Srebalus-Barnes, Alla Polozova, Barbara Rellahan, Daeseok Choi, Richard Burdick, Thomas Stangler and Emily Shacter
      PDA Journal of Pharmaceutical Science and Technology July 2019, 73 (4) 401-416; DOI: https://doi.org/10.5731/pdajpst.2019.010215
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