Probable Scenarios of Process Contamination with Cutibacterium (Propionibacterium) acnes in Mammalian Cell Bioreactor

References

1. 1.↵
   American Society of Mechanical Engineers. ASME BPE-2016: Bioprocessing Equipment. ASME: New York, 2016.
2. 2.↵
   1. Junker B.,
   2. Lester M.,
   3. Leporati J.,
   4. Schmitt J.,
   5. Kovatch M.,
   6. Borysewicz S.,
   7. Maciejak W.,
   8. Seeley A.,
   9. Hesse M.,
   10. Connors N.,
   11. Brix T.,
   12. Creveling E.,
   13. Salmon P.

   Sustainable Reduction of Bioreactor Contamination in an Industrial Fermentation Pilot Plant. J. Biosci. Bioeng. 2006, 102 (4), 251–268.

   OpenUrlCrossRefPubMed
3. 3.↵
   1. Suvarna K.,
   2. Lolas A.,
   3. Hughes P.,
   4. Friedman R.

   Case Studies of Microbial Contamination in Biologic Product Manufacturing. Am. Pharm. Rev. 2011, 14 (1), 50–55.

   OpenUrl
4. 4.↵
   1. Blackwell J.

   Troubleshooting Bacterial Contamination in Bioreactors. BioProcess Online [Online] 2017. https://www.bioprocessonline.com/doc/troubleshooting-bacterial-contamination-in-bioreactors-0001 (May 8, 2019).
5. 5.↵
   1. Kirschbaum J. O.,
   2. Kligman A. M.

   The Pathogenic Role of Corynebacterium acnes in Acne vulgaris. Arch. Dermatol. 1963, 88 (6), 832–833.

   OpenUrlCrossRefPubMedWeb of Science
6. 6.↵
   1. Puhvel S. M.

   Characterization of Corynebacterium acnes. J. Gen. Microbiol. 1968, 50 (2), 313–320.

   OpenUrlCrossRefPubMed
7. 7.↵
   1. Kim J.

   Review of the Innate Immune Response in Acne vulgaris: Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses. Dermatology 2005, 211 (3), 193–198.

   OpenUrlCrossRefPubMed
8. 8.↵
   1. Scholz F. P.,
   2. Kilian M.

   The Natural History of Cutaneous Propionibacteria, and Reclassification of Selected Species within the Genus Propionibacterium to the Proposed Novel Genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov. Int. J. Syst. Evol. Microbiol. 2016, 66 (11), 4422–4432.

   OpenUrlCrossRef
9. 9.↵
   1. Piwowarek K.,
   2. Lipińska E.,
   3. Hać-Szymańczuk E.,
   4. Kieliszek M.,
   5. Ścibisz J.

   Propionibacterium spp.—Source of Propionic Acid, Vitamin B12, and Other Metabolites Important for the Industry. Appl. Microbiol. Biotechnol. 2018, 102, 515–538.

   OpenUrlCrossRef
10. 10.↵
    1. Dréno B.,
    2. Pécastaings S.,
    3. Corvec S.,
    4. Veraldi S.,
    5. Khammari A.,
    6. Roques C.

    Cutibacterium acnes (Propionibacterium acnes) and Acne vulgaris: A Brief Look at the Latest Updates. J. Eur. Acad. Dermatol. Venereol. 2018, 32 (S2), 5–14.

    OpenUrl
11. 11.↵
    1. Acherman Y.,
    2. Goldstein E. J.,
    3. Coenye T.,
    4. Shirtliff M. E.

    Propionibacterium acnes: From Commensal to Opportunistic Biofilm-Associated Implant Pathogen. Clin. Microbiol. Rev. 2014, 27 (3), 419–440.

    OpenUrlAbstract/FREE Full Text
12. 12.↵
    1. Kvich L.,
    2. Jensen P. Ø.,
    3. Justesen U. S.,
    4. Bjarnsholt T.

    Incidence of Propionibacterium acnes in Initially Culture-Negative Thioglycollate Broths—A Prospective Cohort Study at a Danish University Hospital. Clin. Microbiol. Infect. 2016, 22 (11), 941–945.

    OpenUrl
13. 13.↵
    1. Kumar B.,
    2. Pathak R.,
    3. Bertin Mary P.,
    4. Jha D.,
    5. Sardana K.,
    6. Gautam H. K.

    New Insights into Acne Pathogenesis: Exploring the Role of Acne-Associated Microbial Populations. Dermatologica Sinica 2016, 34 (2), 67–73.

    OpenUrl
14. 14.↵
    1. Gallo R. L.,
    2. Nakatsuji T.

    Microbial Symbiosis with the Innate Immune Defense System of the Skin. J. Invest. Dermatol. 2011, 131 (10), 1974–1980.

    OpenUrlCrossRefPubMedWeb of Science
15. 15.↵
    1. Costello E. K.,
    2. Lauber C. L.,
    3. Hamady M.,
    4. Fierer N.,
    5. Gordon J. J.,
    6. Knight R.

    Bacterial Community Variation in Human Body Habitats Across Space and Time. Science 2009, 326 (5960), 1694–1697.

    OpenUrlAbstract/FREE Full Text
16. 16.↵
    1. Bojar R. A.,
    2. Holland K.T.

    Acne and Propionibacterium acnes. Clin. Dermatol. 2004, 22 (5), 375–379.

    OpenUrlCrossRefPubMedWeb of Science
17. 17.↵
    1. Perry A.,
    2. Lambert P.

    Propionibacterium acnes: Infection Beyond the Skin. Expert Review of Anti-Infective Therapy 2011, 9 (12), 1149–1156.

    OpenUrlCrossRefPubMed
18. 18.↵
    1. Jahns A. C.,
    2. Alexeyev O. A.

    Three-Dimensional Distribution of Propionibacterium acnes Biofilms in Human Skin. Exp. Dermatol. 2014, 23(9), 687–689.

    OpenUrl
19. 19.↵
    1. O’Neill A. M.,
    2. Gallo R. L.

    Host-Microbiome Interactions and Recent Progress into Understanding the Biology of Acne vulgaris. Microbiome 2018, 6 (177), 1–16.

    OpenUrlCrossRef
20. 20.↵
    1. Nielsen P. A.

    Role of Reduced Sulfur Compounds in Nutrition of Propionibacterium acnes. J. Clin. Microbiol. 1983, 17 (2), 276-279.

    OpenUrlAbstract/FREE Full Text
21. 21.↵
    1. Tax. G.,
    2. Puskás R.,
    3. Kónya Z.,
    4. Biró T.,
    5. Kemény L.,
    6. Szabó K.

    Propionic Acid Produced by Propionibacterium acnes Strains Contributes to Their Pathogenicity. Acta Derm.-Venereologica 2016, 96 (1), 43–49.

    OpenUrl
22. 22.↵
    1. Shu M.,
    2. Kuo S.,
    3. Wang Y.,
    4. Jiang Y.,
    5. Liu Y.-T.,
    6. Gallo R. L.,
    7. Huang C.-M.

    Porphyrin Metabolism in Human Skin Commensal Propionibacterium acnes Bacteria: Potential Application to Monitor Human Radiation Risk. Curr. Med. Chem. 2013, 20 (4), 562–568.

    OpenUrl
23. 23.↵
    1. Corvec S.

    Clinical and Biological Features of Cutibacterium (Formerly Propionibacterium) avidum, an Underrecognized Microorganism. Clin. Microbiol. Rev. 2018, 31 (3), 1–42.

    OpenUrlCrossRef
24. 24.↵
    1. Portillo E. M.,
    2. Corvec S.,
    3. Borens O.,
    4. Trampuz A.

    Propionibacterium acnes: An Underestimated Pathogen in Implant-Associated Infections. BioMed Res. Int. 2013, 2013 (SI), 804391.

    OpenUrl
25. 25.↵
    1. Midgley M.,
    2. Mohd Noor M. A.

    The interaction of oxygen with Propionibacterium acnes. FEMS Microbiol. Lett. 1984, 23 (2–3), 183–186.

    OpenUrlCrossRefWeb of Science
26. 26.↵
    1. Faille C.,
    2. Jullien C.,
    3. Fontaine F.,
    4. Bellon-Fontaine M.-N.,
    5. Slomianny C.,
    6. Benezech T.

    Adhesion of Bacillus Spores and Escherichia coli Cells to Inert Surfaces: Role of Surface Hydrophobicity. Can. J. Microbiol. 2002, 48 (8), 728–738.

    OpenUrlCrossRefPubMedWeb of Science
27. 27.↵
    1. Knobben B. A. S.,
    2. van der Mei H. C.,
    3. van Horn J. R.,
    4. Busscher H. J.

    Transfer of Bacteria between Biomaterials Surfaces in the Operating Room—An Experimental Study. J. Biomed. Mat. Res. 2007, 80A (4), 790–799.

    OpenUrl
28. 28.↵
    1. Lange-Asschenfeldt B.,
    2. Marenbach D.,
    3. Lang C.,
    4. Patzelt A.,
    5. Ulrich M.,
    6. Maltusch A.,
    7. Terhorst D.,
    8. Stockfleth E.

    Distribution of Bacteria in the Epidermal Layers and Hair Follicles of the Human Skin. Skin Pharmacol. Physiol. 2011, 24 (6), 305–311.

    OpenUrlCrossRefPubMed
29. 29.↵
    1. Salaman-Byron A. L.

    Limitations of Microbial Environmental Monitoring Methods in Cleanrooms. Am. Pharm. Rev. 2018, 21(3), 12–19.

    OpenUrl
30. 30.↵
    1. Schneider M.,
    2. Marison I. W.,
    3. von Stockar U.

    The Importance of Ammonia in Mammalian Cell Culture. J. Biotechnol. 1996, 46 (3), 161–185.

    OpenUrlCrossRefPubMedWeb of Science
31. 31.↵
    1. Dréno B.

    What is New in the Pathophysiology of Acne, An Overview. J. Eur. Acad. Dermatol. Venereol. 2017, 31 Suppl (5), 8–12.

    OpenUrl
32. 32.↵
    1. Tyner H.,
    2. Patel R.

    Propionibacterium Acnes Biofilm-A Sanctuary for Staphlococcus aureus? Anaerobe 2016, 40, 63–67.

    OpenUrl
33. 33.↵
    1. Voisard D.,
    2. Meuwly F.,
    3. Ruffieux P.-A.,
    4. Baer G.,
    5. Kadouri A.

    Potential of Cell Retention Techniques for Large-Scale High-Density Perfusion Culture of Suspended Mammalian Cells. Biotechnol. Bioeng. 2003, 82 (7), 751–765.

    OpenUrlPubMed
34. 34.↵
    1. Li G.,
    2. Tam L.-K.,
    3. Tang J. X.

    Amplified Effect of Brownian Motion in Bacterial Near-Surface Swimming. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(47), 18355–18359.

    OpenUrlAbstract/FREE Full Text
35. 35.↵
    1. Cheung Y. F.,
    2. Fung C. H.,
    3. Walsh C.

    Stereochemistry of Propionyl-Coenzyme A and Pyruvate Carboxylations Catalyzed by Transcarboxylase. Biochemistry 1975, 14 (13), 2981–2986.

    OpenUrl
36. 36.↵
    1. Onadipe A.,
    2. Ulvedal K.

    A Method for the Rapid Detection of Microbial Contaminants in Animal Cell Culture Processes. PDA J. Pharm. Sci. Technol. 2001, 55 (6), 337–345.

    OpenUrlAbstract/FREE Full Text
37. 37.↵
    1. Baumstummler A.,
    2. Chollet R.,
    3. Meder H.,
    4. Rofel C.,
    5. Venchiarutti A.,
    6. Ribault S.

    Detection of Microbial Contaminants in Mammalian Cell Cultures Using a New Fluorescence-Based Staining Method. Lett. Appl. Microbiol. 2010, 51 (6), 671–677.

    OpenUrlPubMed
38. 38.↵
    1. Perkowski C. A.

    Operational Aspects of Bioreactor Contamination Control. J. Parenter. Sci. Technol. 1990, 44 (3), 113–117.

    OpenUrlPubMed
39. 39.↵
    1. Jagani H.,
    2. Hebbar K.,
    3. Gang S. S.,
    4. Raj P. V.,
    5. Rao J. V.

    An Overview of Fermenter and the Design Considerations to Enhance Its Productivity. Pharmacologyonline 2010, 1, 261–301.

    OpenUrl
40. 40.↵
    1. Sandle T.,
    2. Saghee M.R.

    Some Considerations for the Implementation of Disposable Technology and Single-Use Systems in Biopharmaceuticals. J. Commer. Biotechnol. 2011, 17 (4), 319–329.

    OpenUrl
41. 41.↵
    1. Dubiel R.,
    2. Vogel J. D.

    Choosing the Optimal Hygienic Seal for Enhanced Process Performance. Pharmaceutical Engineering 2013, 33 (5), 1–6.

    OpenUrl
42. 42.↵
    1. Suvarna K.,
    2. Lolas A.,
    3. Hughes P.,
    4. Friedman R.

    Case Studies of Microbial Contamination in Biologic Product Manufacturing. Am. Pharm. Rev. [Online] 2011, 14 (1). https://www.americanpharmaceuticalreview.com/Featured-Articles/36755-Case-Studies-of-Microbial-Contamination-in-Biologic-Product-Manufacturing/ (August 8, 2019).
43. 43.↵
    1. Sutton S.

    Successful Microbiological Investigations. Am. Pharm. Rev. [Online] 2011, 14 (2). https://www.americanpharmaceuticalreview.com/Featured-Articles/37190-Successful-Microbiological-Investigations/ (August 8, 2019).
44. 44.↵
    1. Moldenhauer J.

    Conducting Microbial Investigations. Am. Pharm. Rev. [Online] 2015, 15 (5). https://www.americanpharmaceuticalreview.com/Featured-Articles/177313-Conducting-Microbial-Investigations/ (August 8, 2019).
45. 45.↵
    1. McCullough K. Z.,
    2. Moldenhauer J.

    1. McCullough K. Z.,
    2. Moldenhauer J.

    Introduction. In Microbial Risk and Investigations. McCullough K. Z., Moldenhauer J., Eds.; PDA/DHI: Bethesda, MD, 2015; Chapter 1.
46. 46.↵
    1. Gilles N. T.,
    2. Marty E.,
    3. Roesti D.,
    4. Staerk A.,
    5. Goverde M.

    Adoption of FMEA for Microbiological Contamination Risk Assessment to Implement USP Chapter <1115>. Am. Pharm. Rev. [Online] 2017, 20 (6). https://www.americanpharmaceuticalreview.com/Featured-Articles/343500-Adoption-of-FMEA-for-Microbiological-Contamination-Risk-Assessment-to-Implement-USP-Chapter-1115/ (August 8, 2019).