An Investigation to Examine the Effect of the Elastomeric Surface Treatment on Protein Stability

Ranjana Singh; Lloyd Waxman; Liang Fang; Cathy Zhao

doi:10.5731/pdajpst.2020.012120

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An Investigation to Examine the Effect of the Elastomeric Surface Treatment on Protein Stability

Ranjana Singh, Lloyd Waxman, Liang Fang and Cathy Zhao

PDA Journal of Pharmaceutical Science and Technology May 2021, 75 (3) 230-244; DOI: https://doi.org/10.5731/pdajpst.2020.012120

Ranjana Singh

Scientific Insights Lab, West Pharmaceutical Services, Inc., Exton, PA 19341

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Lloyd Waxman

Scientific Insights Lab, West Pharmaceutical Services, Inc., Exton, PA 19341

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Liang Fang

Scientific Insights Lab, West Pharmaceutical Services, Inc., Exton, PA 19341

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Cathy Zhao

Scientific Insights Lab, West Pharmaceutical Services, Inc., Exton, PA 19341

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For correspondence: Cathy.Zhao@westpharma.com

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vol. 75 no. 3 230-244

DOI

https://doi.org/10.5731/pdajpst.2020.012120

PubMed

33443140

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

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Published online May 31, 2021.

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previous version (December 21, 2020 - 09:41).
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Ranjana Singh,
Lloyd Waxman,
Liang Fang and
Cathy Zhao*

Scientific Insights Lab, West Pharmaceutical Services, Inc., Exton, PA 19341

↵* Corresponding Author: Scientific Insights Lab, West Pharmaceutical Services, Inc., 530 Herman O West Drive, Exton, PA 19341; E-mail: Cathy.Zhao{at}westpharma.com

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An Investigation to Examine the Effect of the Elastomeric Surface Treatment on Protein Stability

Ranjana Singh, Lloyd Waxman, Liang Fang, Cathy Zhao

PDA Journal of Pharmaceutical Science and Technology May 2021, 75 (3) 230-244; DOI: 10.5731/pdajpst.2020.012120

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An Investigation to Examine the Effect of the Elastomeric Surface Treatment on Protein Stability

Ranjana Singh, Lloyd Waxman, Liang Fang, Cathy Zhao

PDA Journal of Pharmaceutical Science and Technology May 2021, 75 (3) 230-244; DOI: 10.5731/pdajpst.2020.012120

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Keywords

Drug delivery systems
Elastomers
Stoppers
Siliconization
Lamination
Fluoropolymer
Biotherapeutics
protein aggregation
Protein modification
Protein stability
ß-Lactoglobulin
Human serum albumin
mAb
Antibody
monoclonal antibody
Abatacept
Adalimumab
Immunoglobulin

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