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Article CommentaryCommentary

Enhancement of Cell-Based Vaccine Manufacturing through Process Intensification

William Whitford, Alain M. SourabiÈ and Dushyant B. Varshney
PDA Journal of Pharmaceutical Science and Technology March 2022, 76 (2) 151-162; DOI: https://doi.org/10.5731/pdajpst.2020.012583
William Whitford
1DPS Group, 959 Concord St #100, Framingham, MA 01701; and
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  • For correspondence: William.whitford@dpsgroupglobal.com
Alain M. SourabiÈ
2Procelys by Lesaffre, 103 Rue Jean Jaurès, 94700 Maisons-Alfort, France
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Dushyant B. Varshney
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Article Information

vol. 76 no. 2 151-162
DOI 
https://doi.org/10.5731/pdajpst.2020.012583
PubMed 
34282035

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online April 1, 2022.

Article Versions

  • previous version (July 19, 2021 - 10:39).
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Copyright & Usage 
© PDA, Inc. 2022

Author Information

  1. William Whitford1,*,
  2. Alain M. SourabiÈ2 and
  3. Dushyant B. Varshneyi
  1. 1DPS Group, 959 Concord St #100, Framingham, MA 01701; and
  2. 2Procelys by Lesaffre, 103 Rue Jean Jaurès, 94700 Maisons-Alfort, France
  1. ↵*Corresponding Author: DPS Group, 959 Concord St #100, Framingham, MA 01701. E-mail: William.whitford{at}dpsgroupglobal.com.
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PDA Journal of Pharmaceutical Science and Technology: 76 (2)
PDA Journal of Pharmaceutical Science and Technology
Vol. 76, Issue 2
March/April 2022
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Enhancement of Cell-Based Vaccine Manufacturing through Process Intensification
William Whitford, Alain M. SourabiÈ, Dushyant B. Varshney
PDA Journal of Pharmaceutical Science and Technology Mar 2022, 76 (2) 151-162; DOI: 10.5731/pdajpst.2020.012583

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Enhancement of Cell-Based Vaccine Manufacturing through Process Intensification
William Whitford, Alain M. SourabiÈ, Dushyant B. Varshney
PDA Journal of Pharmaceutical Science and Technology Mar 2022, 76 (2) 151-162; DOI: 10.5731/pdajpst.2020.012583
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  • Article
    • Abstract
    • 1. Introduction
    • 2. Cell-Based Vaccine Production
    • 3. Animal Cells
    • 4. Bacteria
    • 5. Need for Vaccine Process Intensification
    • 6. Intensification Techniques
    • 7. Conclusion
    • Conflict of Interest Declaration
    • Footnotes
    • References
  • Figures & Data
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  • Retrospective Evaluation of Cycled Resin in Viral Clearance Studies - A Multiple Company Collaboration - Post ICH Q5A(R2) Review
  • Addressing Medical Device Extractables and Leachables via Non-Target Analysis (NTA); The Analytical Evaluation Threshold (AET) and Quantitation
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Keywords

  • Intensification
  • process
  • digital
  • optimization
  • production
  • Vaccine
  • Manufacturing
  • efficiency

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