Article CommentaryCommentary
Enhancement of Cell-Based Vaccine Manufacturing through Process Intensification
William Whitford, Alain M. SourabiÈ and Dushyant B. Varshney
PDA Journal of Pharmaceutical Science and Technology March 2022, 76 (2) 151-162; DOI: https://doi.org/10.5731/pdajpst.2020.012583
William Whitford
1DPS Group, 959 Concord St #100, Framingham, MA 01701; and
Alain M. SourabiÈ
2Procelys by Lesaffre, 103 Rue Jean Jaurès, 94700 Maisons-Alfort, France

References
- 1.↵
- Fenn E. A.
- Saunders P.
- 2.↵
- Liddell J. M.
- 3.↵
- Plotkin S. A.,
- Orenstein W. A.,
- Offit P. A.,
- Edwards K. M.
- Gomez P. L.,
- Robinson J. M.
- 4.↵
- 5.↵
- Aslanidi G.,
- Krotova K.
- 6.↵
- Huang X.,
- Wang X.,
- Zhang J.,
- Xia N.,
- Zhao Q.
- 7.↵
- Whitford W.,
- Nelson D.
- 8.↵Intensifying Vaccine Production. https://www.who.int/bulletin/volumes/98/5/20-020520.pdf (accessed January 27, 2022).
- 9.↵
- 10.↵
- Mandal A.
- 11.↵
- 12.↵
- 13.↵
- Tripathi N. K.,
- Shrivastava A.
- 14.↵
- Whitford W
- 15.↵
- Godawat R.,
- Konstantinov K.,
- Rohani M.,
- Warikoo V.
- 16.↵
- Laroche C.,
- Sanraman M. A.,
- Du G.,
- Pandey A.
- Portner R.,
- Barradas O.P.,
- Frahm B.,
- Hass V. C
- 17.↵
- Manzano T.,
- Langer G.
- 18.↵
- Afrin F.,
- Hemey H.,
- Ozbak H.
- María R. R.,
- Arturo C. J.,
- Alicia J. A.,
- Paulina M. G.,
- Gerardo A. O.
- 19.↵
- Adams B.
- 20.↵
- Laroche C.,
- Sanraman M. A.,
- Du G.,
- Pandey A.
- 21.↵Smart Manufacturing with Artificial Intelligence: A Digital Twin Strategy for Accelerated Innovation and Industrial Scale-up. https://xtalks.com/webinars/smart-manufacturing-with-artificial-intelligence-a-digital-twin-strategy-for-accelerated-innovation-and-industrial-scale-up/ (accessed January 27, 2022).
- 22.↵
- 23.↵
- Grumezescu A. M.,
- Holban A. M.
- Mohammadi V.,
- Minaei S.
- 24.↵
- Wang B.,
- Wang Z.,
- Chen T.,
- Zhao X.
- 25.↵AI in Operations Team. Xavier Health Web site. https://www.xavierhealth.org/aio-team (accessed January 27, 2022).
- 26.↵MAST Platform: System for Transferring Samples from Bioreactors to Analytical Devices. http://mastsampling.com/mast-platform/ (accessed January 27, 2022)
- 27.↵Berkeley Lights. https://www.berkeleylights.com (accessed January 27, 2022)
- 28.↵Scale-Up Right First Time With AllegroTM STR Bioreactors. https://go.pall.com/STR-PPC.html?utm_source=google&utm_medium=cpc&utm_campaign=18-02-121-STRBZ&utm_content=text_ad&utm_term=bioreactor&gclid=Cj0KCQiAosmPBhCPARIsAHOen-NAtU7OzIkucZ5aEc1PEgJC7XWWEbmaRfQo9rZEZZoDKpSBaVneOP4aAiq-EALw_wcB (accessed January 27, 2022).
- 29.↵DPS Group and TRIA Congratulate Moderna on ISPE 2019 Facility of the Future Category Award. https://www.dpsgroupglobal.com/news/2019/4/dps-group-and-tria-congratulate-moderna-on–ispe-2019-facility-of-the-future-category-award/ (accessed January 27, 2022).
- 30.↵Univercells NevoLine™ Biomanufacturing Platform. https://www.univercellstech.com/nevoline-biomanufacturing-platform/ (accessed January 27, 2022).
- 31.↵2020 FOYA Category Winner for Facility of the Future & Overall Winner. https://ispe.org/facility-yearawards/winners/2020/facility-future (accessed January 27, 2022).
- 32.↵
- 33.↵
- Jagschies G.,
- Lindskog E.,
- Lacki K.,
- Galliher P.
- Whitford W. G.,
- Lundgren M.,
- Fairbank A.
- 34.↵Production of AAV Vectors Using Suspension Mammalian and Insect Cell Systems. Mammalian and Insect Cell Systems. Pharma’s Almanac Web site. https://www.pharmasalmanac.com/articles/production-of-aav-vectors-using-suspension-mammalian-and-insect-cell-systems (accessed January 27, 2022).
- 35.↵
- Cao W.,
- Cao H.,
- Yi X.,
- Zhuang Y.
In This Issue
PDA Journal of Pharmaceutical Science and Technology
Vol. 76, Issue 2
March/April 2022
Enhancement of Cell-Based Vaccine Manufacturing through Process Intensification
William Whitford, Alain M. SourabiÈ, Dushyant B. Varshney
PDA Journal of Pharmaceutical Science and Technology Mar 2022, 76 (2) 151-162; DOI: 10.5731/pdajpst.2020.012583
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