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Research ArticleResearch

Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro

Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed and Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology September 2023, 77 (5) 340-349; DOI: https://doi.org/10.5731/pdajpst.2021.012654
Cassie Megna
Merck & Co., Inc., Rahway, NJ
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  • For correspondence: cassie.megna@merck.com
Ophelia Wells
Merck & Co., Inc., Rahway, NJ
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Daniel Bonanno
Merck & Co., Inc., Rahway, NJ
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Wail Rasheed
Merck & Co., Inc., Rahway, NJ
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Eduardo Cristofolli
Merck & Co., Inc., Rahway, NJ
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Article Information

vol. 77 no. 5 340-349
DOI 
https://doi.org/10.5731/pdajpst.2021.012654
PubMed 
37188533

Published By 
Parenteral Drug Association (PDA)
Print ISSN 
1079-7440
Online ISSN 
1948-2124
History 
  • Published online October 6, 2023.

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  • previous version (May 15, 2023 - 11:52).
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© PDA, Inc. 2023

Author Information

  1. Cassie Megna*,
  2. Ophelia Wells,
  3. Daniel Bonanno,
  4. Wail Rasheed and
  5. Eduardo Cristofolli
  1. Merck & Co., Inc., Rahway, NJ
  1. ↵*Corresponding Author: Email: cassie.megna{at}merck.com
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PDA Journal of Pharmaceutical Science and Technology: 77 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 77, Issue 5
September/October 2023
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Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro
Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed, Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 340-349; DOI: 10.5731/pdajpst.2021.012654

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Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro
Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed, Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 340-349; DOI: 10.5731/pdajpst.2021.012654
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  • Definition of Particle Visibility Threshold in Parenteral Drug Products—Towards Standardization of Visual Inspection Operator Qualification
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Keywords

  • Prefilled syringes
  • Back pressure
  • Injection
  • Intramuscular
  • Subcutaneous
  • Vaccines
  • Glide force
  • Extrusion force

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