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Research ArticleResearch

Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro

Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed and Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology September 2023, 77 (5) 340-349; DOI: https://doi.org/10.5731/pdajpst.2021.012654
Cassie Megna
Merck & Co., Inc., Rahway, NJ
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Ophelia Wells
Merck & Co., Inc., Rahway, NJ
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Daniel Bonanno
Merck & Co., Inc., Rahway, NJ
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Wail Rasheed
Merck & Co., Inc., Rahway, NJ
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Eduardo Cristofolli
Merck & Co., Inc., Rahway, NJ
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PDA Journal of Pharmaceutical Science and Technology: 77 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 77, Issue 5
September/October 2023
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Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro
Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed, Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 340-349; DOI: 10.5731/pdajpst.2021.012654

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Prefilled Syringe Injection Force Impact Assessment from Back Pressure: An Approach for Testing Syringe Injectability In Situ vs. In Vitro
Cassie Megna, Ophelia Wells, Daniel Bonanno, Wail Rasheed, Eduardo Cristofolli
PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 340-349; DOI: 10.5731/pdajpst.2021.012654
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More in this TOC Section

  • A proof-of-concept study on a universal standard kit to evaluate the risks of inspectors for their foundational ability of visual inspection of injectable drug products
  • Understanding Alignment in the Execution of Extractable Screening Studies Between Laboratories: Results of the ELSIE Lab Practices Sub-Team Industry Surveys
  • Definition of Particle Visibility Threshold in Parenteral Drug Products—Towards Standardization of Visual Inspection Operator Qualification
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Keywords

  • Prefilled syringes
  • Back pressure
  • Injection
  • Intramuscular
  • Subcutaneous
  • Vaccines
  • Glide force
  • Extrusion force

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