Proceedings of the 2023 Viral Clearance Symposium, Session 7: Up- and Downstream Virus Retentive Filtration

Xiaoxiang Zhu; Sean O’Donnell

doi:10.5731/pdajpst.2024.002247

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Proceedings of the 2023 Viral Clearance Symposium, Session 7: Up- and Downstream Virus Retentive Filtration

Xiaoxiang Zhu and Sean O’Donnell

PDA Journal of Pharmaceutical Science and Technology March 2024, 78 (2) 196-205; DOI: https://doi.org/10.5731/pdajpst.2024.002247

Xiaoxiang Zhu

1Pivotal Drug Substance Biologics, Process Development, Amgen Inc., 360 Binney Street, Cambridge, MA 02138; and

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Sean O’Donnell

2BioProcess Research and Development, Eli Lilly and Co., Lilly Corporate Center, Indianapolis, IN 46285

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For correspondence: odonnell_sean_michael@lilly.com

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vol. 78 no. 2 196-205

DOI

https://doi.org/10.5731/pdajpst.2024.002247

PubMed

38609151

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online April 12, 2024.

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Xiaoxiang Zhu¹ and
Sean O’Donnell²,*

¹Pivotal Drug Substance Biologics, Process Development, Amgen Inc., 360 Binney Street, Cambridge, MA 02138; and
²BioProcess Research and Development, Eli Lilly and Co., Lilly Corporate Center, Indianapolis, IN 46285

↵*Corresponding Author: BioProcess Research and Development Eli Lilly and Co., Lilly Corporate Center, Indianapolis, IN 46285. Email: odonnell_sean_michael{at}lilly.com

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PDA Journal of Pharmaceutical Science and Technology

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Proceedings of the 2023 Viral Clearance Symposium, Session 7: Up- and Downstream Virus Retentive Filtration

Xiaoxiang Zhu, Sean O’Donnell

PDA Journal of Pharmaceutical Science and Technology Mar 2024, 78 (2) 196-205; DOI: 10.5731/pdajpst.2024.002247

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Proceedings of the 2023 Viral Clearance Symposium, Session 7: Up- and Downstream Virus Retentive Filtration

Xiaoxiang Zhu, Sean O’Donnell

PDA Journal of Pharmaceutical Science and Technology Mar 2024, 78 (2) 196-205; DOI: 10.5731/pdajpst.2024.002247

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Keywords

Virus filtration
Cell culture media
Pressure/flow interruptions
Viral filter cycling
Continuous/connected process
Viral filter reuse

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