Coring and Fragmentation of Elastomeric Needle Shield in a Pre-Filled Syringe

Sahab Babaee; Sean Teller; Kavin Kowsari; Nikolaos Vasios; Steven C. Persak; Nagi Elabbasi; Guangli Hu

doi:10.5731/pdajpst.2024-003041.1

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Coring and Fragmentation of Elastomeric Needle Shield in a Pre-Filled Syringe

Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi and Guangli Hu

PDA Journal of Pharmaceutical Science and Technology May 2025, 79 (3) 274-284; DOI: https://doi.org/10.5731/pdajpst.2024-003041.1

Sahab Babaee

1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; and

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Sean Teller

2Veryst Engineering LLC, Needham, MA 02494

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Kavin Kowsari

1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; and

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Nikolaos Vasios

2Veryst Engineering LLC, Needham, MA 02494

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Steven C. Persak

1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; and

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Nagi Elabbasi

2Veryst Engineering LLC, Needham, MA 02494

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Guangli Hu

1Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; and

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For correspondence: guangli.hu@merck.com

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vol. 79 no. 3 274-284

DOI

https://doi.org/10.5731/pdajpst.2024-003041.1

PubMed

40300814

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online June 2, 2025.

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previous version (April 29, 2025 - 09:48).
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Sahab Babaee¹,
Sean Teller²,
Kavin Kowsari¹,
Nikolaos Vasios²,
Steven C. Persak¹,
Nagi Elabbasi² and
Guangli Hu^1,*

¹Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; and
²Veryst Engineering LLC, Needham, MA 02494

↵*Corresponding Author: Device Development & Technology, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ 07065; E-mail: guangli.hu{at}merck.com

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PDA Journal of Pharmaceutical Science and Technology

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Coring and Fragmentation of Elastomeric Needle Shield in a Pre-Filled Syringe

Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi, Guangli Hu

PDA Journal of Pharmaceutical Science and Technology May 2025, 79 (3) 274-284; DOI: 10.5731/pdajpst.2024-003041.1

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Coring and Fragmentation of Elastomeric Needle Shield in a Pre-Filled Syringe

Sahab Babaee, Sean Teller, Kavin Kowsari, Nikolaos Vasios, Steven C. Persak, Nagi Elabbasi, Guangli Hu

PDA Journal of Pharmaceutical Science and Technology May 2025, 79 (3) 274-284; DOI: 10.5731/pdajpst.2024-003041.1

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Keywords

prefilled syringe
rigid needle shield
coring
elastomer material
numerical modeling

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