Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System

Galen H. Shi; Sharon L. Shinkle; Ganapathy Gopalrathnam; Xia Dong; Jeffrey D. Hofer; Eric C. Jensen; Natarajan Rajagopalan

doi:10.5731/pdajpst.2017.008169

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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System

Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen and Natarajan Rajagopalan

PDA Journal of Pharmaceutical Science and Technology October 2017, pdajpst.2017.008169; DOI: https://doi.org/10.5731/pdajpst.2017.008169

Galen H. Shi

Eli Lilly and Company

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For correspondence: shi_galen_huaiqiu@lilly.com

Sharon L. Shinkle

Eli Lilly and Company

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For correspondence: shinkle_sharon_l@lilly.com

Ganapathy Gopalrathnam

Eli Lilly and Company

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For correspondence: gopalrathnam_ganapathy@lilly.com

Xia Dong

Eli Lilly and Company

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For correspondence: dong_xia@lilly.com

Jeffrey D. Hofer

Eli Lilly and Company

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For correspondence: hofer_jeffrey_d@lilly.com

Eric C. Jensen

Eli Lilly and Company

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For correspondence: jensen_eric_c@lilly.com

Natarajan Rajagopalan

Eli Lilly and Company

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For correspondence: rajagopalan_natarajan@lilly.com

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PDA Journal of Pharmaceutical Science and Technology

Vol. 79, Issue 1

January/February 2025

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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System

Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen, Natarajan Rajagopalan

PDA Journal of Pharmaceutical Science and Technology Oct 2017, pdajpst.2017.008169; DOI: 10.5731/pdajpst.2017.008169

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Impact of Formulation Variables on Silicone Oil Distribution and Functionality of Prefilled Syringe System

Galen H. Shi, Sharon L. Shinkle, Ganapathy Gopalrathnam, Xia Dong, Jeffrey D. Hofer, Eric C. Jensen, Natarajan Rajagopalan

PDA Journal of Pharmaceutical Science and Technology Oct 2017, pdajpst.2017.008169; DOI: 10.5731/pdajpst.2017.008169

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Keywords

Formulation development
functionality
Glide force
Monoclonal antibodies
Prefilled syringe
silicone

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Parenteral Drug Association, Inc.