CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka; Arnau Gasset; Xavier García-Ortega; David Hubmayr; Joeri B.G. van Wijngaarden; José Luis Montesinos-Seguí; Francisco Valero; Toni Manzano

doi:10.5731/pdajpst.2021.012665

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero and Toni Manzano

PDA Journal of Pharmaceutical Science and Technology September 2022, pdajpst.2021.012665; DOI: https://doi.org/10.5731/pdajpst.2021.012665

Andrej Ondracka

1 Aizon;

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Arnau Gasset

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Xavier García-Ortega

3 QuBilab, Departament de Biociències, Facultat de Ciències i Tecnologia, Universitat de Vic, Universitat Central de Catalunya;

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David Hubmayr

4 CSL Behring AG Process Development & Breakthrough Technologies R&D

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Joeri B.G. van Wijngaarden

1 Aizon;

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For correspondence: joeri.vanwijngaarden@aizon.ai

José Luis Montesinos-Seguí

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Francisco Valero

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Toni Manzano

1 Aizon;

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ORCID record for Toni Manzano
For correspondence: toni.manzano@aizon.ai

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Article Information

pdajpst.2021.012665

DOI

https://doi.org/10.5731/pdajpst.2021.012665

PubMed

36122916

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Received July 1, 2021
Accepted August 30, 2022
Published online September 19, 2022.

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You are currently viewing a previous version of this article (September 19, 2022 - 04:02).
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Author Information

Andrej Ondracka1,
Arnau Gasset2,
Xavier García-Ortega3,
David Hubmayr4,
Joeri B.G. van Wijngaarden1 (joeri.vanwijngaarden{at}aizon.ai),
José Luis Montesinos-Seguí2,
Francisco Valero2 and
Toni Manzano1,5 (toni.manzano{at}aizon.ai)

¹ Aizon;
² Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;
³ QuBilab, Departament de Biociències, Facultat de Ciències i Tecnologia, Universitat de Vic, Universitat Central de Catalunya;
⁴ CSL Behring AG Process Development & Breakthrough Technologies R&D

↵* Corresponding author; email: toni.manzano{at}aizon.ai

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero, Toni Manzano

PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2021.012665; DOI: 10.5731/pdajpst.2021.012665

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero, Toni Manzano

PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2021.012665; DOI: 10.5731/pdajpst.2021.012665

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Keywords

Pichia pastoris
Anomaly detection
Artificial Intelligence
Bioprocess engineering
Bioreactor
machine learning

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