CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka; Arnau Gasset; Xavier García-Ortega; David Hubmayr; Joeri B.G. van Wijngaarden; José Luis Montesinos-Seguí; Francisco Valero; Toni Manzano

doi:10.5731/pdajpst.2021.012665

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero and Toni Manzano

PDA Journal of Pharmaceutical Science and Technology September 2022, pdajpst.2021.012665; DOI: https://doi.org/10.5731/pdajpst.2021.012665

Andrej Ondracka

1 Aizon;

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Arnau Gasset

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Xavier García-Ortega

3 QuBilab, Departament de Biociències, Facultat de Ciències i Tecnologia, Universitat de Vic, Universitat Central de Catalunya;

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David Hubmayr

4 CSL Behring AG Process Development & Breakthrough Technologies R&D

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Joeri B.G. van Wijngaarden

1 Aizon;

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For correspondence: joeri.vanwijngaarden@aizon.ai

José Luis Montesinos-Seguí

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Francisco Valero

2 Department of Chemical, Biological and Environmental Engineering. School of Engineering. Universitat Autònoma de Barcelona;

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Toni Manzano

1 Aizon;

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ORCID record for Toni Manzano
For correspondence: toni.manzano@aizon.ai

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PDA Journal of Pharmaceutical Science and Technology

Vol. 79, Issue 1

January/February 2025

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero, Toni Manzano

PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2021.012665; DOI: 10.5731/pdajpst.2021.012665

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CPV of the Future: AI-powered continued process verification for bioreactor processes

Andrej Ondracka, Arnau Gasset, Xavier García-Ortega, David Hubmayr, Joeri B.G. van Wijngaarden, José Luis Montesinos-Seguí, Francisco Valero, Toni Manzano

PDA Journal of Pharmaceutical Science and Technology Sep 2022, pdajpst.2021.012665; DOI: 10.5731/pdajpst.2021.012665

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Keywords

Pichia pastoris
Anomaly detection
Artificial Intelligence
Bioprocess engineering
Bioreactor
machine learning

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Parenteral Drug Association, Inc.